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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 R78.81

Billable / Specific CC

Bacteremia

R78
Block
0
Synonyms
736
LCDs
15
Payer Policies
0
Linked CPTs

About ICD-10-CM R78.81

ICD-10-CM code R78.81 represents Bacteremia. This is a billable/specific code in the Symptoms, Signs, and Abnormal Findings chapter (block R78). The 2026 edition of ICD-10-CM R78.81 became effective on October 1, 2025.

Coding Tips for R78.81

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

Inpatient DRG impact: CC

R78.81 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Type 1 Excludes

Pure excludes, these codes can never be coded together with R78.81. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • sepsis-code to specified infection

Inpatient DRG Impact, CC

codes Bacteremia. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for R78.81

Local Coverage Determinations (LCDs) from CMS MACs that list R78.81 as a covered diagnosis.

736 LCDs

Showing top 10 of 736 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94660 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94726 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94664 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94618 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94772 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94642 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT G0238 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94004 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94668 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94680 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing R78.81.

15 policies

2 Cigna

Transthoracic Echocardiography in Adults - (0510)
Policy ID: MM_0510
Transthoracic Echocardiography in Children - (0523)
Policy ID: MM_0523

5 Medicare

Billing and Coding: Transesophageal Echocardiography (TEE)
Policy ID: ART-52868
Billing and Coding: Transesophageal Echocardiography (TEE)
Policy ID: ART-56505
Billing and Coding: Echocardiography
Policy ID: ART-56625
Billing and Coding: Intravenous Immunoglobulin (IVIG)
Policy ID: ART-56718
Billing and Coding: Transthoracic Echocardiography (TTE)
Policy ID: ART-56781

CPT Codes Commonly Billed with R78.81

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for R78.81

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert R78.81 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
R78.81 77183 10000
R78.81 7907 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 R78.81, Billing FAQ

Is ICD-10 code R78.81 billable? +

Yes, R78.81 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What codes are Type 1 Excludes for R78.81? +

Type 1 Excludes (never code together with R78.81): sepsis-code to specified infection

Is R78.81 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What ICD-9 codes does R78.81 map to? +

Per CMS GEMs, R78.81 maps to ICD-9 codes: 77183, 7907. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 17, 2026.

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