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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 R16.1

Billable / Specific

Splenomegaly, not elsewhere classified

R16
Block
1
Synonyms
643
LCDs
20
Payer Policies
1
Linked CPTs

About ICD-10-CM R16.1

ICD-10-CM code R16.1 represents Splenomegaly, not elsewhere classified. This is a billable/specific code in the Symptoms, Signs, and Abnormal Findings chapter (block R16). The 2026 edition of ICD-10-CM R16.1 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under R16.1. Per CMS ICD-10-CM Tabular 2026.

  • Splenomegaly NOS

Medicare LCD Coverage for R16.1

Local Coverage Determinations (LCDs) from CMS MACs that list R16.1 as a covered diagnosis.

643 LCDs

Showing top 10 of 643 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74170 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74177 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74160 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74178 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74150 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 72194 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74176 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 72192 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 72193 →
CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Targeted Molecular Panel Tests for Predictive Testing in Cancer
Article ID: 60240, Effective: , 680 covered, 0 non-covered
CPT 81479 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing R16.1.

20 policies

5 Medicare

Billing and Coding: Lab: Flow Cytometry
Policy ID: ART-55717
Billing and Coding: Molecular Pathology Procedures
Policy ID: ART-56199
Billing and Coding: CT of the Abdomen and Pelvis
Policy ID: ART-56421
Billing and Coding: Flow Cytometry
Policy ID: ART-56464
Billing and Coding: Computerized Axial Tomography (CT), Thorax
Policy ID: ART-56580

CPT Codes Commonly Billed with R16.1

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

1 linkages
  • 74177 CT abdomen/pelvis with contrast — abdominal pain, colon cancer staging, liver mets, cholelithiasis, pancreatitis, chronic pancreatitis, pancreatic cancer, hepatomegaly, splenomegaly, abnormal imaging Radiology

Convert R16.1 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
R16.1 7892 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 R16.1, Billing FAQ

Is ICD-10 code R16.1 billable? +

Yes, R16.1 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to R16.1? +

ICD-10 R16.1 includes: Splenomegaly NOS.

What CPT codes are commonly billed with R16.1? +

Procedures frequently paired with R16.1 include: 74177.

What ICD-9 codes does R16.1 map to? +

Per CMS GEMs, R16.1 maps to ICD-9 codes: 7892. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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