ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 Q78.0

Billable / Specific CC

Osteogenesis imperfecta

Q78
Block
2
Synonyms
75
LCDs
11
Payer Policies
0
Linked CPTs

About ICD-10-CM Q78.0

ICD-10-CM code Q78.0 represents Osteogenesis imperfecta. This is a billable/specific code in the Congenital Malformations chapter (block Q78). The 2026 edition of ICD-10-CM Q78.0 became effective on October 1, 2025.

Coding Tips for Q78.0

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

Inpatient DRG impact: CC

Q78.0 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under Q78.0. Per CMS ICD-10-CM Tabular 2026.

  • Fragilitas ossium
  • Osteopsathyrosis

Inpatient DRG Impact, CC

codes Osteogenesis imperfecta. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for Q78.0

Local Coverage Determinations (LCDs) from CMS MACs that list Q78.0 as a covered diagnosis.

75 LCDs

Showing top 10 of 75 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Vitamin D; 25 hydroxy, includes fraction(s), if performed
Article ID: 56841, Effective: 2023-10-01 00:00:00, 759 covered, 1 non-covered
CPT 82306 →
CMS LCD: Billing and Coding: Assays for Vitamins and Metabolic Function
Article ID: 56416, Effective: 2025-10-01 00:00:00, 899 covered, 1 non-covered
CPT 82306 →
CMS LCD: Billing and Coding: Assays for Vitamins and Metabolic Function
Article ID: 56416, Effective: 2025-10-01 00:00:00, 899 covered, 1 non-covered
CPT 82607 →
CMS LCD: Billing and Coding: Assays for Vitamins and Metabolic Function
Article ID: 56416, Effective: 2025-10-01 00:00:00, 899 covered, 1 non-covered
CPT 82746 →
CMS LCD: Billing and Coding: Assays for Vitamins and Metabolic Function
Article ID: 56416, Effective: 2025-10-01 00:00:00, 899 covered, 1 non-covered
CPT 85385 →
CMS LCD: Billing and Coding: Assays for Vitamins and Metabolic Function
Article ID: 56416, Effective: 2025-10-01 00:00:00, 899 covered, 1 non-covered
CPT 83090 →
CMS LCD: Billing and Coding: Assays for Vitamins and Metabolic Function
Article ID: 56416, Effective: 2025-10-01 00:00:00, 899 covered, 1 non-covered
CPT 82652 →
CMS LCD: Billing and Coding: Assays for Vitamins and Metabolic Function
Article ID: 56416, Effective: 2025-10-01 00:00:00, 899 covered, 1 non-covered
CPT 84207 →
CMS LCD: Billing and Coding: Assays for Vitamins and Metabolic Function
Article ID: 56416, Effective: 2025-10-01 00:00:00, 899 covered, 1 non-covered
CPT 86352 →
CMS LCD: Billing and Coding: Assays for Vitamins and Metabolic Function
Article ID: 56416, Effective: 2025-10-01 00:00:00, 899 covered, 1 non-covered
CPT 82379 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing Q78.0.

11 policies

1 Cigna

Vitamin D Testing - (0526) ---- future effective policy
Policy ID: MM_0526

5 Medicare

Billing and Coding: Assays for Vitamins and Metabolic Function
Policy ID: ART-56416
Billing and Coding: Vitamin D; 25 hydroxy, includes fraction(s), if performed
Policy ID: ART-56841
Billing and Coding: Bisphosphonate Drug Therapy
Policy ID: ART-56907
Billing and Coding: Bone Mass Measurement
Policy ID: ART-57132
Billing and Coding: MRI and CT Scans of the Head and Neck
Policy ID: ART-57204

1 Aetna

Wheelchairs and Power Operated Vehicles (Scooters)
Policy ID: CPB-0271

CPT Codes Commonly Billed with Q78.0

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for Q78.0

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert Q78.0 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
Q78.0 75651 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 Q78.0, Billing FAQ

Is ICD-10 code Q78.0 billable? +

Yes, Q78.0 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to Q78.0? +

ICD-10 Q78.0 includes: Fragilitas ossium; Osteopsathyrosis.

Is Q78.0 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What ICD-9 codes does Q78.0 map to? +

Per CMS GEMs, Q78.0 maps to ICD-9 codes: 75651. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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