ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 P24.21

Billable / Specific MCC

Neonatal aspiration of blood with respiratory symptoms

P24
Block
2
Synonyms
70
LCDs
2
Payer Policies
0
Linked CPTs

About ICD-10-CM P24.21

ICD-10-CM code P24.21 represents Neonatal aspiration of blood with respiratory symptoms. This is a billable/specific code in the Perinatal Period chapter (block P24). The 2026 edition of ICD-10-CM P24.21 became effective on October 1, 2025.

Coding Tips for P24.21

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

Inpatient DRG impact: MCC

P24.21 is designated MCC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-MCC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag MCC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under P24.21. Per CMS ICD-10-CM Tabular 2026.

  • Neonatal aspiration of blood with pneumonia
  • Neonatal aspiration of blood with pneumonitis

Use Additional Code

When coding P24.21, also report these additional codes when applicable.

  • code to identify any secondary pulmonary hypertension, if applicable (I27.2-)

Inpatient DRG Impact, MCC

codes Neonatal aspiration of blood with respiratory symptoms. As a Major Complication/Comorbidity (MCC), this can shift the DRG assignment to a higher-weighted category, substantial reimbursement impact.

Medicare LCD Coverage for P24.21

Local Coverage Determinations (LCDs) from CMS MACs that list P24.21 as a covered diagnosis.

70 LCDs

Showing top 10 of 70 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94660 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94726 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94664 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94618 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94772 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94642 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT G0238 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94004 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94668 →
CMS LCD: Billing and Coding: Respiratory Care
Article ID: 57224, Effective: 2026-01-01 00:00:00, 901 covered, 0 non-covered
CPT 94680 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing P24.21.

2 policies

2 Medicare

Billing and Coding: Respiratory Therapy (Respiratory Care)
Policy ID: ART-56717
Billing and Coding: Respiratory Care
Policy ID: ART-57224

CPT Codes Commonly Billed with P24.21

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for P24.21

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert P24.21 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
P24.21 77016 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 P24.21, Billing FAQ

Is ICD-10 code P24.21 billable? +

Yes, P24.21 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to P24.21? +

ICD-10 P24.21 includes: Neonatal aspiration of blood with pneumonia; Neonatal aspiration of blood with pneumonitis.

Is P24.21 a CC or MCC for inpatient DRG? +

Yes, this code is designated as MCC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What ICD-9 codes does P24.21 map to? +

Per CMS GEMs, P24.21 maps to ICD-9 codes: 77016. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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