ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 O99.355

Billable / Specific CC

Diseases of the nervous system complicating the puerperium

O99
Block
0
Synonyms
1
LCDs
1
Payer Policies
0
Linked CPTs

About ICD-10-CM O99.355

ICD-10-CM code O99.355 represents Diseases of the nervous system complicating the puerperium. This is a billable/specific code in the Pregnancy, Childbirth, and Puerperium chapter (block O99). The 2026 edition of ICD-10-CM O99.355 became effective on October 1, 2025.

Coding Tips for O99.355

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

Inpatient DRG impact: CC

O99.355 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Pregnancy chapter (O00-O9A): trimester required

Most O codes require a 7th character indicating trimester (1 = first, 2 = second, 3 = third). Some require fetus identification character. Code O09 (supervision of high-risk pregnancy) is required as a secondary code when applicable.

Inpatient DRG Impact, CC

codes Diseases of the nervous system complicating the puerperium. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for O99.355

Local Coverage Determinations (LCDs) from CMS MACs that list O99.355 as a covered diagnosis.

1 LCDs

Showing top 1. Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Serum Magnesium
Article ID: 57189, Effective: 2025-10-16 00:00:00, 1405 covered, 0 non-covered
CPT 83735 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing O99.355.

1 policies

1 Medicare

Billing and Coding: Serum Magnesium
Policy ID: ART-57189

CPT Codes Commonly Billed with O99.355

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for O99.355

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert O99.355 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
O99.355 64682 10000
O99.355 64684 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 O99.355, Billing FAQ

Is ICD-10 code O99.355 billable? +

Yes, O99.355 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Is O99.355 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What ICD-9 codes does O99.355 map to? +

Per CMS GEMs, O99.355 maps to ICD-9 codes: 64682, 64684. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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