ICD-10 O45.01
Non-Billable HeaderPremature separation of placenta with afibrinogenemia
About ICD-10-CM O45.01
ICD-10-CM code O45.01 represents Premature separation of placenta with afibrinogenemia. This is a non-billable header code in the Pregnancy, Childbirth, and Puerperium chapter (block O45). The 2026 edition of ICD-10-CM O45.01 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.
Coding Tips for O45.01
Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.
Most O codes require a 7th character indicating trimester (1 = first, 2 = second, 3 = third). Some require fetus identification character. Code O09 (supervision of high-risk pregnancy) is required as a secondary code when applicable.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under O45.01. Per CMS ICD-10-CM Tabular 2026.
- Premature separation of placenta with hypofibrinogenemia
Medicare LCD Coverage for O45.01
Local Coverage Determinations (LCDs) from CMS MACs that list O45.01 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing O45.01.
Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but O45.01 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.
CPT Codes Commonly Billed with O45.01
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Codes Adjacent To O45.01
Other codes in section O30-O48 (Maternal care related to the fetus and amniotic cavity and possible delivery problems).
ICD-10 O45.01, Billing FAQ
Is ICD-10 code O45.01 billable? +
No, O45.01 is a non-billable header code. Use a more specific child code from block O45 when submitting claims.
What other names or terms map to O45.01? +
ICD-10 O45.01 includes: Premature separation of placenta with hypofibrinogenemia.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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