ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 M45.4

Billable / Specific HCC v28: 40

Ankylosing spondylitis of thoracic region

M45
Block
0
Synonyms
229
LCDs
9
Payer Policies
0
Linked CPTs

About ICD-10-CM M45.4

ICD-10-CM code M45.4 represents Ankylosing spondylitis of thoracic region. This is a billable/specific code in the Musculoskeletal and Connective Tissue chapter (block M45). The 2026 edition of ICD-10-CM M45.4 became effective on October 1, 2025.

Coding Tips for M45.4

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

M45.4 is a CMS-HCC v28 risk-adjustment code (category 40). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 40
ESRD-HCC
Category 40
RxHCC (Part D)
Category 40

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for M45.4

Local Coverage Determinations (LCDs) from CMS MACs that list M45.4 as a covered diagnosis.

229 LCDs

Showing top 10 of 229 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Sedimentation Rate, Erythrocyte
Article ID: 57657, Effective: 2024-10-01 00:00:00, 1430 covered, 1 non-covered
CPT 85651 →
CMS LCD: Billing and Coding: Sedimentation Rate, Erythrocyte
Article ID: 57657, Effective: 2024-10-01 00:00:00, 1430 covered, 1 non-covered
CPT 85652 →
CMS LCD: Billing and Coding: Infliximab
Article ID: 56432, Effective: 2026-01-01 00:00:00, 406 covered, 0 non-covered
CPT J1745 →
CMS LCD: Billing and Coding: Infliximab
Article ID: 56432, Effective: 2026-01-01 00:00:00, 406 covered, 0 non-covered
CPT Q5103 →
CMS LCD: Billing and Coding: Infliximab
Article ID: 56432, Effective: 2026-01-01 00:00:00, 406 covered, 0 non-covered
CPT Q5121 →
CMS LCD: Billing and Coding: Infliximab
Article ID: 56432, Effective: 2026-01-01 00:00:00, 406 covered, 0 non-covered
CPT Q5104 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 88189 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 86360 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 86361 →
CMS LCD: Billing and Coding: Lab: Flow Cytometry
Article ID: 57689, Effective: 2025-11-06 00:00:00, 1518 covered, 0 non-covered
CPT 88187 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing M45.4.

9 policies

5 Medicare

Billing and Coding: Infliximab and biosimilars
Policy ID: ART-52423
Billing and Coding: Outpatient Occupational Therapy
Policy ID: ART-53064
Billing and Coding: Outpatient Physical Therapy
Policy ID: ART-53065
Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions
Policy ID: ART-55639
Billing and Coding: Infliximab
Policy ID: ART-56432

CPT Codes Commonly Billed with M45.4

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for M45.4

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert M45.4 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
M45.4 7200 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 M45.4, Billing FAQ

Is ICD-10 code M45.4 billable? +

Yes, M45.4 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does M45.4 affect Medicare Advantage HCC risk adjustment? +

Yes. M45.4 maps to CMS-HCC v28 category 40. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What ICD-9 codes does M45.4 map to? +

Per CMS GEMs, M45.4 maps to ICD-9 codes: 7200. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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