ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 I82.221

Billable / Specific HCC v28: 108 MCC

Chronic embolism and thrombosis of inferior vena cava

I82
Block
0
Synonyms
283
LCDs
19
Payer Policies
5
Linked CPTs

About ICD-10-CM I82.221

ICD-10-CM code I82.221 represents Chronic embolism and thrombosis of inferior vena cava. This is a billable/specific code in the Circulatory System chapter (block I82). The 2026 edition of ICD-10-CM I82.221 became effective on October 1, 2025.

Coding Tips for I82.221

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

I82.221 is a CMS-HCC v28 risk-adjustment code (category 108). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inpatient DRG impact: MCC

I82.221 is designated MCC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-MCC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag MCC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 108
ESRD-HCC
Category 108
RxHCC (Part D)
Category 108

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Inpatient DRG Impact, MCC

codes Chronic embolism and thrombosis of inferior vena cava. As a Major Complication/Comorbidity (MCC), this can shift the DRG assignment to a higher-weighted category, substantial reimbursement impact.

Medicare LCD Coverage for I82.221

Local Coverage Determinations (LCDs) from CMS MACs that list I82.221 as a covered diagnosis.

283 LCDs

Showing top 10 of 283 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Magnetic Resonance Angiography
Article ID: 56775, Effective: 2025-10-01 00:00:00, 1311 covered, 0 non-covered
CPT C8918 →
CMS LCD: Billing and Coding: Magnetic Resonance Angiography
Article ID: 56775, Effective: 2025-10-01 00:00:00, 1311 covered, 0 non-covered
CPT C8936 →
CMS LCD: Billing and Coding: Magnetic Resonance Angiography
Article ID: 56775, Effective: 2025-10-01 00:00:00, 1311 covered, 0 non-covered
CPT C8910 →
CMS LCD: Billing and Coding: Magnetic Resonance Angiography
Article ID: 56775, Effective: 2025-10-01 00:00:00, 1311 covered, 0 non-covered
CPT 70548 →
CMS LCD: Billing and Coding: Magnetic Resonance Angiography
Article ID: 56775, Effective: 2025-10-01 00:00:00, 1311 covered, 0 non-covered
CPT C8913 →
CMS LCD: Billing and Coding: Magnetic Resonance Angiography
Article ID: 56775, Effective: 2025-10-01 00:00:00, 1311 covered, 0 non-covered
CPT C8912 →
CMS LCD: Billing and Coding: Magnetic Resonance Angiography
Article ID: 56775, Effective: 2025-10-01 00:00:00, 1311 covered, 0 non-covered
CPT C8914 →
CMS LCD: Billing and Coding: Magnetic Resonance Angiography
Article ID: 56775, Effective: 2025-10-01 00:00:00, 1311 covered, 0 non-covered
CPT 70547 →
CMS LCD: Billing and Coding: Magnetic Resonance Angiography
Article ID: 56775, Effective: 2025-10-01 00:00:00, 1311 covered, 0 non-covered
CPT C8901 →
CMS LCD: Billing and Coding: Magnetic Resonance Angiography
Article ID: 56775, Effective: 2025-10-01 00:00:00, 1311 covered, 0 non-covered
CPT C8902 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing I82.221.

19 policies

3 Aetna

Magnetic Resonance Angiography (MRA) and Magnetic Resonance Venography (MRV) - Medical Clinical Policy Bulletins | Aetna
Policy ID: CPB-0094
Magnetic Resonance Imaging of the Cardiovascular System - Cardiac MRI
Policy ID: CPB-0520
Thrombectomy Systems
Policy ID: CPB-0568

5 Medicare

Billing and Coding: Transesophageal Echocardiography (TEE)
Policy ID: ART-52868
Billing and Coding: Endovenous Stenting
Policy ID: ART-56414
Billing and Coding: Transesophageal Echocardiography (TEE)
Policy ID: ART-56505
Billing and Coding: Biomarkers Overview
Policy ID: ART-56541
Billing and Coding: Computerized Axial Tomography (CT), Thorax
Policy ID: ART-56580

CPT Codes Commonly Billed with I82.221

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

5 linkages
  • 37238 CMS LCD: Billing and Coding: Endovenous Stenting CMS LCD
  • 37239 CMS LCD: Billing and Coding: Endovenous Stenting CMS LCD
  • 37183 CMS LCD: Billing and Coding: Endovenous Stenting CMS LCD
  • 37182 CMS LCD: Billing and Coding: Endovenous Stenting CMS LCD
  • 81490 CMS LCD: Billing and Coding: Biomarkers Overview CMS LCD

Convert I82.221 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
I82.221 4532 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

Codes Adjacent To I82.221

Other codes in section I80-I89 (Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified).

I80 Phlebitis and thrombophlebitis (non-billable) I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities (non-billable) I80.00 Phlebitis and thrombophlebitis of superficial vessels of unspecified lower extremity I80.01 Phlebitis and thrombophlebitis of superficial vessels of right lower extremity I80.02 Phlebitis and thrombophlebitis of superficial vessels of left lower extremity I80.03 Phlebitis and thrombophlebitis of superficial vessels of lower extremities, bilateral I80.1 Phlebitis and thrombophlebitis of femoral vein (non-billable) I80.10 Phlebitis and thrombophlebitis of unspecified femoral vein I80.11 Phlebitis and thrombophlebitis of right femoral vein I80.12 Phlebitis and thrombophlebitis of left femoral vein I80.13 Phlebitis and thrombophlebitis of femoral vein, bilateral I80.2 Phlebitis and thrombophlebitis of other and unspecified deep vessels of lower extremities (non-billable) I80.20 Phlebitis and thrombophlebitis of unspecified deep vessels of lower extremities (non-billable) I80.201 Phlebitis and thrombophlebitis of unspecified deep vessels of right lower extremity I80.202 Phlebitis and thrombophlebitis of unspecified deep vessels of left lower extremity I80.203 Phlebitis and thrombophlebitis of unspecified deep vessels of lower extremities, bilateral I80.209 Phlebitis and thrombophlebitis of unspecified deep vessels of unspecified lower extremity I80.21 Phlebitis and thrombophlebitis of iliac vein (non-billable) I80.211 Phlebitis and thrombophlebitis of right iliac vein I80.212 Phlebitis and thrombophlebitis of left iliac vein

ICD-10 I82.221, Billing FAQ

Is ICD-10 code I82.221 billable? +

Yes, I82.221 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does I82.221 affect Medicare Advantage HCC risk adjustment? +

Yes. I82.221 maps to CMS-HCC v28 category 108. Capture this diagnosis annually for accurate Medicare Advantage risk score.

Is I82.221 a CC or MCC for inpatient DRG? +

Yes, this code is designated as MCC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What CPT codes are commonly billed with I82.221? +

Procedures frequently paired with I82.221 include: 37238, 37239, 37183, 37182, 81490.

What ICD-9 codes does I82.221 map to? +

Per CMS GEMs, I82.221 maps to ICD-9 codes: 4532. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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