ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 I25.759

Billable / Specific HCC v28: 88 CC

Atherosclerosis of native coronary artery of transplanted heart with unspecified angina pectoris

I25
Block
0
Synonyms
450
LCDs
25
Payer Policies
4
Linked CPTs

About ICD-10-CM I25.759

ICD-10-CM code I25.759 represents Atherosclerosis of native coronary artery of transplanted heart with unspecified angina pectoris. This is a billable/specific code in the Circulatory System chapter (block I25). The 2026 edition of ICD-10-CM I25.759 became effective on October 1, 2025.

Coding Tips for I25.759

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

I25.759 is a CMS-HCC v28 risk-adjustment code (category 88). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inpatient DRG impact: CC

I25.759 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 88
ESRD-HCC
Category 88
RxHCC (Part D)
Category 88

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Inpatient DRG Impact, CC

codes Atherosclerosis of native coronary artery of transplanted heart with unspecified angina pectoris. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for I25.759

Local Coverage Determinations (LCDs) from CMS MACs that list I25.759 as a covered diagnosis.

450 LCDs

Showing top 10 of 450 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Transesophageal Echocardiogram
Article ID: 57179, Effective: 2026-02-26 00:00:00, 421 covered, 1 non-covered
CPT 93313 →
CMS LCD: Billing and Coding: Transesophageal Echocardiogram
Article ID: 57179, Effective: 2026-02-26 00:00:00, 421 covered, 1 non-covered
CPT 93312 →
CMS LCD: Billing and Coding: Transesophageal Echocardiogram
Article ID: 57179, Effective: 2026-02-26 00:00:00, 421 covered, 1 non-covered
CPT 93318 →
CMS LCD: Billing and Coding: Transesophageal Echocardiogram
Article ID: 57179, Effective: 2026-02-26 00:00:00, 421 covered, 1 non-covered
CPT 93317 →
CMS LCD: Billing and Coding: Transesophageal Echocardiogram
Article ID: 57179, Effective: 2026-02-26 00:00:00, 421 covered, 1 non-covered
CPT C8927 →
CMS LCD: Billing and Coding: Transesophageal Echocardiogram
Article ID: 57179, Effective: 2026-02-26 00:00:00, 421 covered, 1 non-covered
CPT C8925 →
CMS LCD: Billing and Coding: Transesophageal Echocardiogram
Article ID: 57179, Effective: 2026-02-26 00:00:00, 421 covered, 1 non-covered
CPT 93314 →
CMS LCD: Billing and Coding: Transesophageal Echocardiogram
Article ID: 57179, Effective: 2026-02-26 00:00:00, 421 covered, 1 non-covered
CPT C8926 →
CMS LCD: Billing and Coding: Transesophageal Echocardiogram
Article ID: 57179, Effective: 2026-02-26 00:00:00, 421 covered, 1 non-covered
CPT 93316 →
CMS LCD: Billing and Coding: Transesophageal Echocardiogram
Article ID: 57179, Effective: 2026-02-26 00:00:00, 421 covered, 1 non-covered
CPT 93315 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing I25.759.

25 policies

3 Cigna

Duplex Scan of Extracranial Arteries - (0542)
Policy ID: MM_0542
Plasma Brain Natriuretic Peptide in the Outpatient Setting - (0028)
Policy ID: MM_0028
Transthoracic Echocardiography in Adults - (0510)
Policy ID: MM_0510

5 Medicare

Billing and Coding: Cardiac Catheterization and Coronary Angiography
Policy ID: ART-52850
Billing and Coding: Cardiac Computed Tomography (CCT) and Coronary Computed Tomography Angiography (CCTA)
Policy ID: ART-56451
Billing and Coding: Cardiac Radionuclide Imaging
Policy ID: ART-56476
Billing and Coding: Cardiovascular Nuclear Medicine
Policy ID: ART-56494
Billing and Coding: Cardiac Catheterization and Coronary Angiography
Policy ID: ART-56500

CPT Codes Commonly Billed with I25.759

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

4 linkages
  • 75574 CMS LCD: Billing and Coding: Coronary Computed Tomography Angiography (CCTA) CMS LCD
  • 75573 CMS LCD: Billing and Coding: Coronary Computed Tomography Angiography (CCTA) CMS LCD
  • 75572 CMS LCD: Billing and Coding: Coronary Computed Tomography Angiography (CCTA) CMS LCD
  • 75571 CMS LCD: Billing and Coding: Coronary Computed Tomography Angiography (CCTA) CMS LCD

Convert I25.759 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
I25.759 4139 10112
I25.759 41406 10111

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 I25.759, Billing FAQ

Is ICD-10 code I25.759 billable? +

Yes, I25.759 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does I25.759 affect Medicare Advantage HCC risk adjustment? +

Yes. I25.759 maps to CMS-HCC v28 category 88. Capture this diagnosis annually for accurate Medicare Advantage risk score.

Is I25.759 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What CPT codes are commonly billed with I25.759? +

Procedures frequently paired with I25.759 include: 75574, 75573, 75572, 75571.

What ICD-9 codes does I25.759 map to? +

Per CMS GEMs, I25.759 maps to ICD-9 codes: 4139, 41406. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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