ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 F32.81

Billable / Specific

Premenstrual dysphoric disorder

F32
Block
0
Synonyms
315
LCDs
12
Payer Policies
0
Linked CPTs

About ICD-10-CM F32.81

ICD-10-CM code F32.81 represents Premenstrual dysphoric disorder. This is a billable/specific code in the Mental, Behavioral, and Neurodevelopmental chapter (block F32). The 2026 edition of ICD-10-CM F32.81 became effective on October 1, 2025.

Type 1 Excludes

Pure excludes, these codes can never be coded together with F32.81. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • premenstrual tension syndrome (N94.3)

Medicare LCD Coverage for F32.81

Local Coverage Determinations (LCDs) from CMS MACs that list F32.81 as a covered diagnosis.

315 LCDs

Showing top 10 of 315 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81227 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81328 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81335 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 0071U →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81383 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81418 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 0073U →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81283 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81408 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81355 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing F32.81.

12 policies

5 Medicare

Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse Testing
Policy ID: ART-56645
Billing and Coding: Psychiatric Partial Hospitalization Programs
Policy ID: ART-56850
Billing and Coding: Psychiatry and Psychology Services
Policy ID: ART-56937
Billing and Coding: MRI and CT Scans of the Head and Neck
Policy ID: ART-57204
Billing and Coding: Psychiatry and Psychology Services
Policy ID: ART-57480

1 Aetna

Premenstrual Syndrome and Premenstrual Dysphoric Disorder
Policy ID: CPB-0512

CPT Codes Commonly Billed with F32.81

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for F32.81

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert F32.81 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
F32.81 6254 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 F32.81, Billing FAQ

Is ICD-10 code F32.81 billable? +

Yes, F32.81 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What codes are Type 1 Excludes for F32.81? +

Type 1 Excludes (never code together with F32.81): premenstrual tension syndrome (N94.3)

What ICD-9 codes does F32.81 map to? +

Per CMS GEMs, F32.81 maps to ICD-9 codes: 6254. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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