ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 F12.21

Billable / Specific HCC v28: 55

Cannabis dependence, in remission

F12
Block
4
Synonyms
181
LCDs
8
Payer Policies
0
Linked CPTs

About ICD-10-CM F12.21

ICD-10-CM code F12.21 represents Cannabis dependence, in remission. This is a billable/specific code in the Mental, Behavioral, and Neurodevelopmental chapter (block F12). The 2026 edition of ICD-10-CM F12.21 became effective on October 1, 2025.

Coding Tips for F12.21

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

F12.21 is a CMS-HCC v28 risk-adjustment code (category 55). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under F12.21. Per CMS ICD-10-CM Tabular 2026.

  • Cannabis use disorder, moderate, in early remission
  • Cannabis use disorder, moderate, in sustained remission
  • Cannabis use disorder, severe, in early remission
  • Cannabis use disorder, severe, in sustained remission

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 55
ESRD-HCC
Category 55
RxHCC (Part D)
Category 55

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for F12.21

Local Coverage Determinations (LCDs) from CMS MACs that list F12.21 as a covered diagnosis.

181 LCDs

Showing top 10 of 181 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse Testing
Article ID: 56645, Effective: 2024-10-01 00:00:00, 1310 covered, 1 non-covered
CPT G0480 →
CMS LCD: Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse Testing
Article ID: 56645, Effective: 2024-10-01 00:00:00, 1310 covered, 1 non-covered
CPT G0481 →
CMS LCD: Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse Testing
Article ID: 56645, Effective: 2024-10-01 00:00:00, 1310 covered, 1 non-covered
CPT G0482 →
CMS LCD: Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse Testing
Article ID: 56645, Effective: 2024-10-01 00:00:00, 1310 covered, 1 non-covered
CPT G0483 →
CMS LCD: Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse Testing
Article ID: 56645, Effective: 2024-10-01 00:00:00, 1310 covered, 1 non-covered
CPT 80305 →
CMS LCD: Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse Testing
Article ID: 56645, Effective: 2024-10-01 00:00:00, 1310 covered, 1 non-covered
CPT G0659 →
CMS LCD: Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse Testing
Article ID: 56645, Effective: 2024-10-01 00:00:00, 1310 covered, 1 non-covered
CPT 80307 →
CMS LCD: Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse Testing
Article ID: 56645, Effective: 2024-10-01 00:00:00, 1310 covered, 1 non-covered
CPT 80306 →
CMS LCD: Billing and Coding: Psychiatric Diagnostic Evaluation and Psychotherapy Services
Article ID: 57520, Effective: 2025-01-01 00:00:00, 582 covered, 1 non-covered
CPT 90847 →
CMS LCD: Billing and Coding: Psychiatric Diagnostic Evaluation and Psychotherapy Services
Article ID: 57520, Effective: 2025-01-01 00:00:00, 582 covered, 1 non-covered
CPT G0560 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing F12.21.

8 policies

5 Medicare

Billing and Coding: Controlled Substance Monitoring and Drugs of Abuse Testing
Policy ID: ART-56645
Billing and Coding: Urine Drug Testing
Policy ID: ART-56818
Billing and Coding: Psychiatric Partial Hospitalization Programs
Policy ID: ART-57053
Billing and Coding: Psychiatric Codes
Policy ID: ART-57130
Billing and Coding: Monitored Anesthesia Care
Policy ID: ART-57361

CPT Codes Commonly Billed with F12.21

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for F12.21

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert F12.21 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
F12.21 30433 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 F12.21, Billing FAQ

Is ICD-10 code F12.21 billable? +

Yes, F12.21 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to F12.21? +

ICD-10 F12.21 includes: Cannabis use disorder, moderate, in early remission; Cannabis use disorder, moderate, in sustained remission; Cannabis use disorder, severe, in early remission, and 1 more clinical synonyms.

Does F12.21 affect Medicare Advantage HCC risk adjustment? +

Yes. F12.21 maps to CMS-HCC v28 category 55. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What ICD-9 codes does F12.21 map to? +

Per CMS GEMs, F12.21 maps to ICD-9 codes: 30433. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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