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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E88.2

Billable / Specific

Lipomatosis, not elsewhere classified

E88
Block
2
Synonyms
51
LCDs
6
Payer Policies
10
Linked CPTs

About ICD-10-CM E88.2

ICD-10-CM code E88.2 represents Lipomatosis, not elsewhere classified. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E88). The 2026 edition of ICD-10-CM E88.2 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under E88.2. Per CMS ICD-10-CM Tabular 2026.

  • Lipomatosis NOS
  • Lipomatosis (Check) dolorosa [Dercum]

Medicare LCD Coverage for E88.2

Local Coverage Determinations (LCDs) from CMS MACs that list E88.2 as a covered diagnosis.

51 LCDs

Showing top 10 of 51 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Article ID: 57559, Effective: 2025-10-01 00:00:00, 179 covered, 0 non-covered
CPT 86141 →
CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Article ID: 57559, Effective: 2025-10-01 00:00:00, 179 covered, 0 non-covered
CPT 83090 →
CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Article ID: 57559, Effective: 2025-10-01 00:00:00, 179 covered, 0 non-covered
CPT 83704 →
CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Article ID: 57559, Effective: 2025-10-01 00:00:00, 179 covered, 0 non-covered
CPT 83719 →
CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Article ID: 57559, Effective: 2025-10-01 00:00:00, 179 covered, 0 non-covered
CPT 83880 →
CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Article ID: 57559, Effective: 2025-10-01 00:00:00, 179 covered, 0 non-covered
CPT 83700 →
CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Article ID: 57559, Effective: 2025-10-01 00:00:00, 179 covered, 0 non-covered
CPT 83695 →
CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Article ID: 57559, Effective: 2025-10-01 00:00:00, 179 covered, 0 non-covered
CPT 82610 →
CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Article ID: 57559, Effective: 2025-10-01 00:00:00, 179 covered, 0 non-covered
CPT 83701 →
CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Article ID: 57559, Effective: 2025-10-01 00:00:00, 179 covered, 0 non-covered
CPT 83721 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E88.2.

6 policies

5 Medicare

Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Policy ID: ART-56943
Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Policy ID: ART-57037
Billing and Coding: Electrocardiograms
Policy ID: ART-57326
Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Policy ID: ART-57386
Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Policy ID: ART-57559

1 Aetna

Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) of the Spine
Policy ID: CPB-0236

CPT Codes Commonly Billed with E88.2

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

10 linkages
  • 83090 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83700 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 82172 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 86141 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83701 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83719 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83721 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83698 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83695 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83704 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD

Convert E88.2 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
E88.2 2728 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 E88.2, Billing FAQ

Is ICD-10 code E88.2 billable? +

Yes, E88.2 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to E88.2? +

ICD-10 E88.2 includes: Lipomatosis NOS; Lipomatosis (Check) dolorosa [Dercum].

What CPT codes are commonly billed with E88.2? +

Procedures frequently paired with E88.2 include: 83090, 83700, 82172, 86141, 83701.

What ICD-9 codes does E88.2 map to? +

Per CMS GEMs, E88.2 maps to ICD-9 codes: 2728. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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