ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E88.1

Non-Billable Header

Lipodystrophy, not elsewhere classified

E88
Block
0
Synonyms
0
LCDs
1
Payer Policies
0
Linked CPTs

About ICD-10-CM E88.1

ICD-10-CM code E88.1 represents Lipodystrophy, not elsewhere classified. This is a non-billable header code in the Endocrine, Nutritional, and Metabolic chapter (block E88). The 2026 edition of ICD-10-CM E88.1 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.

Type 1 Excludes

Pure excludes, these codes can never be coded together with E88.1. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • Whipple's disease (K90.81)

Medicare LCD Coverage for E88.1

Local Coverage Determinations (LCDs) from CMS MACs that list E88.1 as a covered diagnosis.

No Medicare LCDs reference E88.1 as covered

This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E88.1.

1 policies

1 Aetna

Growth Hormone (GH) and Growth Hormone Antagonists
Policy ID: CPB-0170

CPT Codes Commonly Billed with E88.1

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for E88.1

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert E88.1 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
E88.1 2726 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 E88.1, Billing FAQ

Is ICD-10 code E88.1 billable? +

No, E88.1 is a non-billable header code. Use a more specific child code from block E88 when submitting claims.

What codes are Type 1 Excludes for E88.1? +

Type 1 Excludes (never code together with E88.1): Whipple's disease (K90.81)

What ICD-9 codes does E88.1 map to? +

Per CMS GEMs, E88.1 maps to ICD-9 codes: 2726. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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