ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E87.1

Billable / Specific CC

Hypo-osmolality and hyponatremia

E87
Block
1
Synonyms
82
LCDs
4
Payer Policies
3
Linked CPTs

About ICD-10-CM E87.1

ICD-10-CM code E87.1 represents Hypo-osmolality and hyponatremia. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E87). The 2026 edition of ICD-10-CM E87.1 became effective on October 1, 2025.

Coding Tips for E87.1

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

Inpatient DRG impact: CC

E87.1 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under E87.1. Per CMS ICD-10-CM Tabular 2026.

  • Sodium [Na] deficiency

Type 1 Excludes

Pure excludes, these codes can never be coded together with E87.1. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • syndrome of inappropriate secretion of antidiuretic hormone (E22.2)

Inpatient DRG Impact, CC

codes Hypo-osmolality and hyponatremia. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for E87.1

Local Coverage Determinations (LCDs) from CMS MACs that list E87.1 as a covered diagnosis.

82 LCDs

Showing top 10 of 82 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Electrocardiograms
Article ID: 57326, Effective: 2025-11-06 00:00:00, 2736 covered, 0 non-covered
CPT 93000 →
CMS LCD: Billing and Coding: Electrocardiograms
Article ID: 57326, Effective: 2025-11-06 00:00:00, 2736 covered, 0 non-covered
CPT 93041 →
CMS LCD: Billing and Coding: Electrocardiograms
Article ID: 57326, Effective: 2025-11-06 00:00:00, 2736 covered, 0 non-covered
CPT 93040 →
CMS LCD: Billing and Coding: Electrocardiograms
Article ID: 57326, Effective: 2025-11-06 00:00:00, 2736 covered, 0 non-covered
CPT 93042 →
CMS LCD: Billing and Coding: Electrocardiograms
Article ID: 57326, Effective: 2025-11-06 00:00:00, 2736 covered, 0 non-covered
CPT 93005 →
CMS LCD: Billing and Coding: Electrocardiograms
Article ID: 57326, Effective: 2025-11-06 00:00:00, 2736 covered, 0 non-covered
CPT 93010 →
CMS LCD: Billing and Coding: Serum Magnesium
Article ID: 57189, Effective: 2025-10-16 00:00:00, 1405 covered, 0 non-covered
CPT 83735 →
CMS LCD: Billing and Coding: Monitored Anesthesia Care
Article ID: 57361, Effective: 2026-01-01 00:00:00, 2006 covered, 0 non-covered
CPT 01860 →
CMS LCD: Billing and Coding: Monitored Anesthesia Care
Article ID: 57361, Effective: 2026-01-01 00:00:00, 2006 covered, 0 non-covered
CPT 00400 →
CMS LCD: Billing and Coding: Monitored Anesthesia Care
Article ID: 57361, Effective: 2026-01-01 00:00:00, 2006 covered, 0 non-covered
CPT 01782 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E87.1.

4 policies

4 Medicare

Billing and Coding: Serum Magnesium
Policy ID: ART-57189
Billing and Coding: MRI and CT Scans of the Head and Neck
Policy ID: ART-57204
Billing and Coding: Electrocardiograms
Policy ID: ART-57326
Billing and Coding: Monitored Anesthesia Care
Policy ID: ART-57361

CPT Codes Commonly Billed with E87.1

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

3 linkages
  • 80053 Comprehensive metabolic panel — diabetes, HTN, CKD, hyperlipidemia, electrolyte disorders, anemia, thyroid, prediabetes, abnormal labs, routine exam, screening Laboratory
  • 80048 Basic metabolic panel — diabetes, HTN, CKD, electrolyte disorders, abnormal labs, routine exam, HF, dehydration Laboratory
  • 90935 Hemodialysis single — ESRD, CKD stage 5, acute kidney injury, hyperkalemia, hypokalemia, hypernatremia, drug overdose, unspecified kidney failure Nephrology

Convert E87.1 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
E87.1 2761 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 E87.1, Billing FAQ

Is ICD-10 code E87.1 billable? +

Yes, E87.1 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to E87.1? +

ICD-10 E87.1 includes: Sodium [Na] deficiency.

What codes are Type 1 Excludes for E87.1? +

Type 1 Excludes (never code together with E87.1): syndrome of inappropriate secretion of antidiuretic hormone (E22.2)

Is E87.1 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What CPT codes are commonly billed with E87.1? +

Procedures frequently paired with E87.1 include: 80053, 80048, 90935.

What ICD-9 codes does E87.1 map to? +

Per CMS GEMs, E87.1 maps to ICD-9 codes: 2761. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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