ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E78.6

Billable / Specific

Lipoprotein deficiency

E78
Block
7
Synonyms
155
LCDs
8
Payer Policies
0
Linked CPTs

About ICD-10-CM E78.6

ICD-10-CM code E78.6 represents Lipoprotein deficiency. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E78). The 2026 edition of ICD-10-CM E78.6 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under E78.6. Per CMS ICD-10-CM Tabular 2026.

  • Abetalipoproteinemia
  • Depressed HDL cholesterol
  • High-density lipoprotein deficiency
  • Hypoalphalipoproteinemia
  • Hypobetalipoproteinemia (familial)
  • Lecithin cholesterol acyltransferase deficiency
  • Tangier disease

Medicare LCD Coverage for E78.6

Local Coverage Determinations (LCDs) from CMS MACs that list E78.6 as a covered diagnosis.

155 LCDs

Showing top 10 of 155 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Nerve Conduction Studies and Electromyography
Article ID: 57668, Effective: 2025-10-01 00:00:00, 1629 covered, 0 non-covered
CPT 95909 →
CMS LCD: Billing and Coding: Nerve Conduction Studies and Electromyography
Article ID: 57668, Effective: 2025-10-01 00:00:00, 1629 covered, 0 non-covered
CPT 95887 →
CMS LCD: Billing and Coding: Nerve Conduction Studies and Electromyography
Article ID: 57668, Effective: 2025-10-01 00:00:00, 1629 covered, 0 non-covered
CPT 95912 →
CMS LCD: Billing and Coding: Nerve Conduction Studies and Electromyography
Article ID: 57668, Effective: 2025-10-01 00:00:00, 1629 covered, 0 non-covered
CPT 95999 →
CMS LCD: Billing and Coding: Nerve Conduction Studies and Electromyography
Article ID: 57668, Effective: 2025-10-01 00:00:00, 1629 covered, 0 non-covered
CPT 95910 →
CMS LCD: Billing and Coding: Nerve Conduction Studies and Electromyography
Article ID: 57668, Effective: 2025-10-01 00:00:00, 1629 covered, 0 non-covered
CPT 95870 →
CMS LCD: Billing and Coding: Nerve Conduction Studies and Electromyography
Article ID: 57668, Effective: 2025-10-01 00:00:00, 1629 covered, 0 non-covered
CPT 95860 →
CMS LCD: Billing and Coding: Nerve Conduction Studies and Electromyography
Article ID: 57668, Effective: 2025-10-01 00:00:00, 1629 covered, 0 non-covered
CPT 95913 →
CMS LCD: Billing and Coding: Nerve Conduction Studies and Electromyography
Article ID: 57668, Effective: 2025-10-01 00:00:00, 1629 covered, 0 non-covered
CPT 95869 →
CMS LCD: Billing and Coding: Nerve Conduction Studies and Electromyography
Article ID: 57668, Effective: 2025-10-01 00:00:00, 1629 covered, 0 non-covered
CPT G0255 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E78.6.

8 policies

5 Medicare

Billing and Coding: Nerve Conduction Studies and Electromyography
Policy ID: ART-54969
Billing and Coding: Nerve Conduction Studies and Electromyography
Policy ID: ART-56619
Billing and Coding: Nerve Conduction Studies and Electromyography
Policy ID: ART-57307
Billing and Coding: Electrocardiograms
Policy ID: ART-57326
Billing and Coding: Nerve Conduction Studies and Electromyography
Policy ID: ART-57478

2 Aetna

Cardiovascular Disease Risk Tests
Policy ID: CPB-0381
Nerve Conduction Studies
Policy ID: CPB-0502

CPT Codes Commonly Billed with E78.6

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for E78.6

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert E78.6 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
E78.6 2725 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 E78.6, Billing FAQ

Is ICD-10 code E78.6 billable? +

Yes, E78.6 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to E78.6? +

ICD-10 E78.6 includes: Abetalipoproteinemia; Depressed HDL cholesterol; High-density lipoprotein deficiency, and 4 more clinical synonyms.

What ICD-9 codes does E78.6 map to? +

Per CMS GEMs, E78.6 maps to ICD-9 codes: 2725. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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