ICD-10 E78.1
Billable / SpecificPure hyperglyceridemia
About ICD-10-CM E78.1
ICD-10-CM code E78.1 represents Pure hyperglyceridemia. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E78). The 2026 edition of ICD-10-CM E78.1 became effective on October 1, 2025.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under E78.1. Per CMS ICD-10-CM Tabular 2026.
- Elevated fasting triglycerides
- Endogenous hyperglyceridemia
- Fredrickson's hyperlipoproteinemia, type IV
- Hyperlipidemia, group B
- Hyperprebetalipoproteinemia
- Very-low-density-lipoprotein-type [VLDL] hyperlipoproteinemia
Medicare LCD Coverage for E78.1
Local Coverage Determinations (LCDs) from CMS MACs that list E78.1 as a covered diagnosis.
Showing top 10 of 214 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing E78.1.
5 Medicare
1 Aetna
CPT Codes Commonly Billed with E78.1
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
- 80061 Lipid panel — hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, CAD, HTN, diabetes, lipid screening, family hx heart disease, obesity Laboratory
- 83090 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
- 83700 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
- 82172 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
- 86141 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
- 83701 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
- 83719 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
- 83721 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
- 83698 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
- 83695 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
Convert E78.1 to ICD-9-CM
Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.
| ICD-10 | ICD-9 | Mapping Flags |
|---|---|---|
| E78.1 | 2721 | 00000 |
Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).
Codes Adjacent To E78.1
Other codes in section E70-E88 (Metabolic disorders).
ICD-10 E78.1, Billing FAQ
Is ICD-10 code E78.1 billable? +
Yes, E78.1 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to E78.1? +
ICD-10 E78.1 includes: Elevated fasting triglycerides; Endogenous hyperglyceridemia; Fredrickson's hyperlipoproteinemia, type IV, and 3 more clinical synonyms.
What CPT codes are commonly billed with E78.1? +
Procedures frequently paired with E78.1 include: 80061, 83090, 83700, 82172, 86141.
What ICD-9 codes does E78.1 map to? +
Per CMS GEMs, E78.1 maps to ICD-9 codes: 2721. Useful for legacy data review and historical claim analysis.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on July 16, 2026.
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