PAYER READY CREDENTIALING & COMPLIANCE
ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E78.019

Billable / Specific

Familial hypercholesterolemia, unspecified

E78
Block
1
Synonyms
198
LCDs
12
Payer Policies
10
Linked CPTs

About ICD-10-CM E78.019

ICD-10-CM code E78.019 represents Familial hypercholesterolemia, unspecified. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E78). The 2026 edition of ICD-10-CM E78.019 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under E78.019. Per CMS ICD-10-CM Tabular 2026.

  • Familial hypercholesterolemia NOS

Medicare LCD Coverage for E78.019

Local Coverage Determinations (LCDs) from CMS MACs that list E78.019 as a covered diagnosis.

198 LCDs

Showing top 10 of 198 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81227 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81328 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81335 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 0071U →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81383 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81418 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 0073U →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81283 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81408 →
CMS LCD: Billing and Coding: Pharmacogenomics Testing
Article ID: 58801, Effective: 2026-01-01 00:00:00, 578 covered, 0 non-covered
CPT 81355 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E78.019.

12 policies

5 Medicare

Billing and Coding: Therapeutic Apheresis for Familial Hypercholesterolemia
Policy ID: ART-56289
Billing and Coding: Ophthalmic Angiography (Fluorescein and Indocyanine Green)
Policy ID: ART-56774
Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Policy ID: ART-56943
Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
Policy ID: ART-57037
Billing and Coding: Cardiovascular Stress Testing, Including Exercise and/or Pharmacological Stress and Stress Echocardiography
Policy ID: ART-57183

1 Aetna

Genetic Testing
Policy ID: CPB-0140

CPT Codes Commonly Billed with E78.019

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

10 linkages
  • 83090 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83700 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 82172 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 86141 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83701 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83719 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83721 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83698 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83695 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD
  • 83704 CMS LCD: Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment CMS LCD

ICD-10 E78.019, Billing FAQ

Is ICD-10 code E78.019 billable? +

Yes, E78.019 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to E78.019? +

ICD-10 E78.019 includes: Familial hypercholesterolemia NOS.

What CPT codes are commonly billed with E78.019? +

Procedures frequently paired with E78.019 include: 83090, 83700, 82172, 86141, 83701.

Get the full PayerReady toolkit

Free access to CPT/ICD-10 lookup, denial appeals, fee comparator, and claim auditing with credentialing enrollment.

Start free →

Run this code through our claim audit tool

Check NCCI bundling, MUE limits, and modifier logic before submission.

Try the auditor →

Did this page help?

Quick signal so we know what to improve.

Thanks!

If you want a code reference page that doesn't exist yet, email coding@payerready.com.

Sorry to hear that.

Tell us what's missing or wrong: coding@payerready.com. We respond within 5 business days.

Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

Powered by 11K CPT · 98K ICD-10 · 860K MPFS rates · 4.5M NCCI edits · 9.5M NPIs. Our data methodology · About our coding team

Every month un-credentialed is revenue you never bill

Sign up free, add your first provider, and watch the pipeline start moving this week.

Ask CredBrain

Answers from your credentialing team's verified knowledge base

Hi, I'm CredBrain. I answer from your credentialing team's verified knowledge base: payer join paths, state rules, timelines, associate billing, and enrollment workflows. If I don't have a verified answer, I'll say so and point you to your team. What would you like to know?

Try asking