ICD-10 E78.0
Non-Billable HeaderPure hypercholesterolemia
About ICD-10-CM E78.0
ICD-10-CM code E78.0 represents Pure hypercholesterolemia. This is a non-billable header code in the Endocrine, Nutritional, and Metabolic chapter (block E78). The 2026 edition of ICD-10-CM E78.0 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.
Medicare LCD Coverage for E78.0
Local Coverage Determinations (LCDs) from CMS MACs that list E78.0 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing E78.0.
Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but E78.0 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.
CPT Codes Commonly Billed with E78.0
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
- 80061 Lipid panel — hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, CAD, HTN, diabetes, lipid screening, family hx heart disease, obesity Laboratory
Codes Adjacent To E78.0
Other codes in section E70-E88 (Metabolic disorders).
ICD-10 E78.0, Billing FAQ
Is ICD-10 code E78.0 billable? +
No, E78.0 is a non-billable header code. Use a more specific child code from block E78 when submitting claims.
What CPT codes are commonly billed with E78.0? +
Procedures frequently paired with E78.0 include: 80061.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on July 16, 2026.
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