ICD-10 E74.810
Billable / Specific HCC v28: 23 CCGlucose transporter protein type 1 deficiency
About ICD-10-CM E74.810
ICD-10-CM code E74.810 represents Glucose transporter protein type 1 deficiency. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E74). The 2026 edition of ICD-10-CM E74.810 became effective on October 1, 2025.
Coding Tips for E74.810
Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.
E74.810 is a CMS-HCC v28 risk-adjustment code (category 23). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.
E74.810 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under E74.810. Per CMS ICD-10-CM Tabular 2026.
- De Vivo syndrome
- Glucose transport defect, blood-brain barrier
- Glut1 deficiency
- GLUT1 deficiency syndrome 1, infantile onset
- GLUT1 deficiency syndrome 2, childhood onset
Medicare Advantage HCC Impact
Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.
Inpatient DRG Impact, CC
codes Glucose transporter protein type 1 deficiency. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.
Medicare LCD Coverage for E74.810
Local Coverage Determinations (LCDs) from CMS MACs that list E74.810 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing E74.810.
Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but E74.810 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.
CPT Codes Commonly Billed with E74.810
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Codes Adjacent To E74.810
Other codes in section E70-E88 (Metabolic disorders).
ICD-10 E74.810, Billing FAQ
Is ICD-10 code E74.810 billable? +
Yes, E74.810 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to E74.810? +
ICD-10 E74.810 includes: De Vivo syndrome; Glucose transport defect, blood-brain barrier; Glut1 deficiency, and 2 more clinical synonyms.
Does E74.810 affect Medicare Advantage HCC risk adjustment? +
Yes. E74.810 maps to CMS-HCC v28 category 23. Capture this diagnosis annually for accurate Medicare Advantage risk score.
Is E74.810 a CC or MCC for inpatient DRG? +
Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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