ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E71.50

Billable / Specific HCC v28: 23 CC

Peroxisomal disorder, unspecified

E71
Block
0
Synonyms
11
LCDs
3
Payer Policies
0
Linked CPTs

About ICD-10-CM E71.50

ICD-10-CM code E71.50 represents Peroxisomal disorder, unspecified. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E71). The 2026 edition of ICD-10-CM E71.50 became effective on October 1, 2025.

Coding Tips for E71.50

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

E71.50 is a CMS-HCC v28 risk-adjustment code (category 23). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inpatient DRG impact: CC

E71.50 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 23
ESRD-HCC
Category 23
RxHCC (Part D)
Category 23

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Inpatient DRG Impact, CC

codes Peroxisomal disorder, unspecified. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.

Medicare LCD Coverage for E71.50

Local Coverage Determinations (LCDs) from CMS MACs that list E71.50 as a covered diagnosis.

11 LCDs

Showing top 10 of 11 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Article ID: 56773, Effective: 2025-10-01 00:00:00, 1653 covered, 1 non-covered
CPT 95928 →
CMS LCD: Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Article ID: 56773, Effective: 2025-10-01 00:00:00, 1653 covered, 1 non-covered
CPT 92651 →
CMS LCD: Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Article ID: 56773, Effective: 2025-10-01 00:00:00, 1653 covered, 1 non-covered
CPT 95926 →
CMS LCD: Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Article ID: 56773, Effective: 2025-10-01 00:00:00, 1653 covered, 1 non-covered
CPT 92653 →
CMS LCD: Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Article ID: 56773, Effective: 2025-10-01 00:00:00, 1653 covered, 1 non-covered
CPT 95938 →
CMS LCD: Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Article ID: 56773, Effective: 2025-10-01 00:00:00, 1653 covered, 1 non-covered
CPT 92652 →
CMS LCD: Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Article ID: 56773, Effective: 2025-10-01 00:00:00, 1653 covered, 1 non-covered
CPT 95929 →
CMS LCD: Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Article ID: 56773, Effective: 2025-10-01 00:00:00, 1653 covered, 1 non-covered
CPT 95927 →
CMS LCD: Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Article ID: 56773, Effective: 2025-10-01 00:00:00, 1653 covered, 1 non-covered
CPT 95930 →
CMS LCD: Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Article ID: 56773, Effective: 2025-10-01 00:00:00, 1653 covered, 1 non-covered
CPT 95925 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E71.50.

3 policies

2 Cigna

Electrodiagnostic Testing (EMG/NCV) - (CPG129)
Policy ID: CPG129_EMG_NCV_SSEP
Infant Nutritional Formula - (0136)
Policy ID: MM_0136

1 Medicare

Billing and Coding: Neurophysiology Evoked Potentials (NEPs)
Policy ID: ART-56773

CPT Codes Commonly Billed with E71.50

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for E71.50

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert E71.50 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
E71.50 27786 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 E71.50, Billing FAQ

Is ICD-10 code E71.50 billable? +

Yes, E71.50 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does E71.50 affect Medicare Advantage HCC risk adjustment? +

Yes. E71.50 maps to CMS-HCC v28 category 23. Capture this diagnosis annually for accurate Medicare Advantage risk score.

Is E71.50 a CC or MCC for inpatient DRG? +

Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.

What ICD-9 codes does E71.50 map to? +

Per CMS GEMs, E71.50 maps to ICD-9 codes: 27786. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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