ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E29.1

Billable / Specific

Testicular hypofunction

E29
Block
3
Synonyms
16
LCDs
7
Payer Policies
7
Linked CPTs

About ICD-10-CM E29.1

ICD-10-CM code E29.1 represents Testicular hypofunction. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E29). The 2026 edition of ICD-10-CM E29.1 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under E29.1. Per CMS ICD-10-CM Tabular 2026.

  • Defective biosynthesis of testicular androgen NOS
  • 5-delta-Reductase deficiency (with male pseudohermaphroditism)
  • Testicular hypogonadism NOS

Type 1 Excludes

Pure excludes, these codes can never be coded together with E29.1. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • postprocedural testicular hypofunction (E89.5)

Use Additional Code

When coding E29.1, also report these additional codes when applicable.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Medicare LCD Coverage for E29.1

Local Coverage Determinations (LCDs) from CMS MACs that list E29.1 as a covered diagnosis.

16 LCDs

Showing top 10 of 16 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT J1071 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT J3145 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT 84410 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT 84403 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT 11980 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT J3121 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT 96372 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT J3490 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT J1072 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 57615, Effective: 2025-10-16 00:00:00, 11 covered, 0 non-covered
CPT J1071 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E29.1.

7 policies

2 Medicare

Billing and Coding: Treatment of Males with Low Testosterone
Policy ID: ART-57615
Billing and Coding: Treatment of Males with Low Testosterone
Policy ID: ART-58828

5 Aetna

Bone Mass Measurements
Policy ID: CPB-0134
Infertility
Policy ID: CPB-0327
Varicocele: Selected Treatments
Policy ID: CPB-0413
Testosterone Undecanoate (Aveed) Injection
Policy ID: CPB-0528
Therapeutic Phlebotomy
Policy ID: CPB-0652

CPT Codes Commonly Billed with E29.1

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

7 linkages
  • J3145 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • 84403 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • 84410 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • J1072 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • 11980 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • J1071 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • J3121 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD

Convert E29.1 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
E29.1 2572 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 E29.1, Billing FAQ

Is ICD-10 code E29.1 billable? +

Yes, E29.1 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to E29.1? +

ICD-10 E29.1 includes: Defective biosynthesis of testicular androgen NOS; 5-delta-Reductase deficiency (with male pseudohermaphroditism); Testicular hypogonadism NOS.

What codes are Type 1 Excludes for E29.1? +

Type 1 Excludes (never code together with E29.1): postprocedural testicular hypofunction (E89.5)

What CPT codes are commonly billed with E29.1? +

Procedures frequently paired with E29.1 include: J3145, 84403, 84410, J1072, 11980.

What ICD-9 codes does E29.1 map to? +

Per CMS GEMs, E29.1 maps to ICD-9 codes: 2572. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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