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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E28.39

Billable / Specific

Other primary ovarian failure

E28
Block
2
Synonyms
42
LCDs
8
Payer Policies
13
Linked CPTs

About ICD-10-CM E28.39

ICD-10-CM code E28.39 represents Other primary ovarian failure. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E28). The 2026 edition of ICD-10-CM E28.39 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under E28.39. Per CMS ICD-10-CM Tabular 2026.

  • Decreased estrogen
  • Resistant ovary syndrome

Medicare LCD Coverage for E28.39

Local Coverage Determinations (LCDs) from CMS MACs that list E28.39 as a covered diagnosis.

42 LCDs

Showing top 10 of 42 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74170 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74177 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74160 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74178 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74150 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 72194 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 74176 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 72192 →
CMS LCD: Billing and Coding: CT of the Abdomen and Pelvis
Article ID: 56421, Effective: 2025-11-01 00:00:00, 5389 covered, 0 non-covered
CPT 72193 →
CMS LCD: Billing and Coding: Bariatric Surgery Coverage
Article ID: 53026, Effective: 2026-01-01 00:00:00, 553 covered, 0 non-covered
CPT 43846 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E28.39.

8 policies

4 Medicare

Billing and Coding: Bariatric Surgery Coverage
Policy ID: ART-53026
Billing and Coding: CT of the Abdomen and Pelvis
Policy ID: ART-56421
Billing and Coding: Bone Mass Measurement
Policy ID: ART-57132
Billing and Coding: Bone Mass Measurement
Policy ID: ART-59040

4 Aetna

Bone Mass Measurements
Policy ID: CPB-0134
Genetic Counseling
Policy ID: CPB-0189
Infertility
Policy ID: CPB-0327
Progestins
Policy ID: CPB-0510

CPT Codes Commonly Billed with E28.39

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

13 linkages
  • 77081 CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
  • 0556T CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
  • 78350 CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
  • 0554T CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
  • 77085 CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
  • 0558T CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
  • 0555T CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
  • 0557T CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
  • 77078 CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
  • 76977 CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD

Convert E28.39 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
E28.39 25639 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 E28.39, Billing FAQ

Is ICD-10 code E28.39 billable? +

Yes, E28.39 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to E28.39? +

ICD-10 E28.39 includes: Decreased estrogen; Resistant ovary syndrome.

What CPT codes are commonly billed with E28.39? +

Procedures frequently paired with E28.39 include: 77081, 0556T, 78350, 0554T, 77085.

What ICD-9 codes does E28.39 map to? +

Per CMS GEMs, E28.39 maps to ICD-9 codes: 25639. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 17, 2026.

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