ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 E23.1

Billable / Specific HCC v28: 23

Drug-induced hypopituitarism

E23
Block
0
Synonyms
146
LCDs
10
Payer Policies
7
Linked CPTs

About ICD-10-CM E23.1

ICD-10-CM code E23.1 represents Drug-induced hypopituitarism. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E23). The 2026 edition of ICD-10-CM E23.1 became effective on October 1, 2025.

Coding Tips for E23.1

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

E23.1 is a CMS-HCC v28 risk-adjustment code (category 23). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Use Additional Code

When coding E23.1, also report these additional codes when applicable.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 23
ESRD-HCC
Category 23
RxHCC (Part D)
Category 23

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for E23.1

Local Coverage Determinations (LCDs) from CMS MACs that list E23.1 as a covered diagnosis.

146 LCDs

Showing top 10 of 146 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Visual Fields Testing
Article ID: 56551, Effective: 2025-10-01 00:00:00, 1427 covered, 0 non-covered
CPT 92082 →
CMS LCD: Billing and Coding: Visual Fields Testing
Article ID: 56551, Effective: 2025-10-01 00:00:00, 1427 covered, 0 non-covered
CPT 92083 →
CMS LCD: Billing and Coding: Visual Fields Testing
Article ID: 56551, Effective: 2025-10-01 00:00:00, 1427 covered, 0 non-covered
CPT 92081 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT J1071 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT J3145 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT 84410 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT 84403 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT 11980 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT J3121 →
CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone
Article ID: 58828, Effective: 2026-04-02 00:00:00, 39 covered, 0 non-covered
CPT 96372 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing E23.1.

10 policies

5 Medicare

Billing and Coding: Visual Fields Testing
Policy ID: ART-56551
Billing and Coding: CT of the Head
Policy ID: ART-56612
Billing and Coding: Thoracic Aortography and Carotid, Vertebral, and Subclavian Angiography
Policy ID: ART-56631
Billing and Coding: Visual Fields Testing
Policy ID: ART-56799
Billing and Coding: Aortography and Peripheral Angiography
Policy ID: ART-57056

1 Aetna

Growth Hormone (GH) and Growth Hormone Antagonists
Policy ID: CPB-0170

CPT Codes Commonly Billed with E23.1

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

7 linkages
  • J3145 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • 84403 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • 84410 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • J1072 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • 11980 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • J1071 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
  • J3121 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD

Convert E23.1 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
E23.1 2537 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 E23.1, Billing FAQ

Is ICD-10 code E23.1 billable? +

Yes, E23.1 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

Does E23.1 affect Medicare Advantage HCC risk adjustment? +

Yes. E23.1 maps to CMS-HCC v28 category 23. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What CPT codes are commonly billed with E23.1? +

Procedures frequently paired with E23.1 include: J3145, 84403, 84410, J1072, 11980.

What ICD-9 codes does E23.1 map to? +

Per CMS GEMs, E23.1 maps to ICD-9 codes: 2537. Useful for legacy data review and historical claim analysis.

Get the full PayerReady toolkit

Free access to CPT/ICD-10 lookup, denial appeals, fee comparator, and claim auditing with credentialing enrollment.

Start free →

Run this code through our claim audit tool

Check NCCI bundling, MUE limits, and modifier logic before submission.

Try the auditor →

Did this page help?

Quick signal so we know what to improve.

Thanks!

If you want a code reference page that doesn't exist yet, email coding@payerready.com.

Sorry to hear that.

Tell us what's missing or wrong: coding@payerready.com. We respond within 5 business days.

Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

Powered by 11K CPT · 98K ICD-10 · 860K MPFS rates · 4.5M NCCI edits · 9.5M NPIs. Our data methodology · About our coding team

Faster Approvals

Ready to Cut Your Enrollment Timeline in Half?

Join providers in all 50 states who handed off credentialing to a dedicated specialist. Create your free account in minutes and start enrolling the same day.

All 50 States Covered
No Long-Term Contracts
HIPAA HIPAA Compliant Platform
Dedicated Specialist Included