ICD-10 E23.0
Billable / Specific HCC v28: 23 CCHypopituitarism
About ICD-10-CM E23.0
ICD-10-CM code E23.0 represents Hypopituitarism. This is a billable/specific code in the Endocrine, Nutritional, and Metabolic chapter (block E23). The 2026 edition of ICD-10-CM E23.0 became effective on October 1, 2025.
Coding Tips for E23.0
Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.
E23.0 is a CMS-HCC v28 risk-adjustment code (category 23). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.
E23.0 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under E23.0. Per CMS ICD-10-CM Tabular 2026.
- Fertile eunuch syndrome
- Hypogonadotropic hypogonadism
- Idiopathic growth hormone deficiency
- Isolated deficiency of gonadotropin
- Isolated deficiency of growth hormone
- Isolated deficiency of pituitary hormone
- Kallmann's syndrome
- Lorain-Levi short stature
- Necrosis of pituitary gland (postpartum)
- Panhypopituitarism
- Pituitary cachexia
- Pituitary insufficiency NOS
- Pituitary short stature
- Sheehan's syndrome
- Simmonds' disease
Use Additional Code
When coding E23.0, also report these additional codes when applicable.
- code, if applicable, for associated cachexia (E88.A)
Medicare Advantage HCC Impact
Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.
Inpatient DRG Impact, CC
codes Hypopituitarism. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.
Medicare LCD Coverage for E23.0
Local Coverage Determinations (LCDs) from CMS MACs that list E23.0 as a covered diagnosis.
Showing top 10 of 172 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing E23.0.
5 Medicare
5 Aetna
CPT Codes Commonly Billed with E23.0
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
- J3145 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
- 84403 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
- 84410 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
- J1072 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
- 11980 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
- J1071 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
- J3121 CMS LCD: Billing and Coding: Treatment of Males with Low Testosterone CMS LCD
- 77081 CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
- 0556T CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
- 78350 CMS LCD: Billing and Coding: Bone Mass Measurement CMS LCD
Convert E23.0 to ICD-9-CM
Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.
| ICD-10 | ICD-9 | Mapping Flags |
|---|---|---|
| E23.0 | 2532 | 10000 |
| E23.0 | 2533 | 10000 |
| E23.0 | 6281 | 10000 |
Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).
Codes Adjacent To E23.0
Other codes in section E20-E35 (Disorders of other endocrine glands).
ICD-10 E23.0, Billing FAQ
Is ICD-10 code E23.0 billable? +
Yes, E23.0 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to E23.0? +
ICD-10 E23.0 includes: Fertile eunuch syndrome; Hypogonadotropic hypogonadism; Idiopathic growth hormone deficiency, and 12 more clinical synonyms.
Does E23.0 affect Medicare Advantage HCC risk adjustment? +
Yes. E23.0 maps to CMS-HCC v28 category 23. Capture this diagnosis annually for accurate Medicare Advantage risk score.
Is E23.0 a CC or MCC for inpatient DRG? +
Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.
What CPT codes are commonly billed with E23.0? +
Procedures frequently paired with E23.0 include: J3145, 84403, 84410, J1072, 11980.
What ICD-9 codes does E23.0 map to? +
Per CMS GEMs, E23.0 maps to ICD-9 codes: 2532, 2533, 6281. Useful for legacy data review and historical claim analysis.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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