ICD-10 D68.021
Billable / Specific HCC v28: 48 CCVon Willebrand disease, type 2B
About ICD-10-CM D68.021
ICD-10-CM code D68.021 represents Von Willebrand disease, type 2B. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D68). The 2026 edition of ICD-10-CM D68.021 became effective on October 1, 2025.
Coding Tips for D68.021
Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.
D68.021 is a CMS-HCC v28 risk-adjustment code (category 48). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.
D68.021 is designated CC for MS-DRG grouping. On inpatient claims, this code can shift the DRG to the with-CC variant when documented as a present-on-admission secondary diagnosis. Hospital CDI programs flag CC opportunities during chart review. Failure to capture this code may leave 30 to 80 percent of the inpatient stay revenue unrealized.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under D68.021. Per CMS ICD-10-CM Tabular 2026.
- Qualitative defects of von Willebrand factor with high-molecular-weight von Willebrand factor loss
- Qualitative defects of von Willebrand factor with hyper-adhesive forms
- Qualitative defects of von Willebrand factor with increased affinity for platelet glycoprotein lb
Medicare Advantage HCC Impact
Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.
Inpatient DRG Impact, CC
codes Von Willebrand disease, type 2B. As a Complication/Comorbidity (CC), this contributes to DRG severity adjustment when documented alongside the principal diagnosis.
Medicare LCD Coverage for D68.021
Local Coverage Determinations (LCDs) from CMS MACs that list D68.021 as a covered diagnosis.
Showing top 10 of 65 total . Click a CPT for full coverage scope.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing D68.021.
4 Medicare
2 Aetna
CPT Codes Commonly Billed with D68.021
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
- J7187 CMS LCD: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 CMS LCD
- J7201 CMS LCD: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 CMS LCD
- J7179 CMS LCD: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 CMS LCD
- J7194 CMS LCD: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 CMS LCD
- J7180 CMS LCD: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 CMS LCD
- J7175 CMS LCD: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 CMS LCD
- J7189 CMS LCD: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 CMS LCD
- J7209 CMS LCD: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 CMS LCD
- J7186 CMS LCD: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 CMS LCD
- J7182 CMS LCD: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 CMS LCD
Codes Adjacent To D68.021
Other codes in section D65-D69 (Coagulation defects, purpura and other hemorrhagic conditions).
ICD-10 D68.021, Billing FAQ
Is ICD-10 code D68.021 billable? +
Yes, D68.021 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.
What other names or terms map to D68.021? +
ICD-10 D68.021 includes: Qualitative defects of von Willebrand factor with high-molecular-weight von Willebrand factor loss; Qualitative defects of von Willebrand factor with hyper-adhesive forms; Qualitative defects of von Willebrand factor with increased affinity for platelet glycoprotein lb.
Does D68.021 affect Medicare Advantage HCC risk adjustment? +
Yes. D68.021 maps to CMS-HCC v28 category 48. Capture this diagnosis annually for accurate Medicare Advantage risk score.
Is D68.021 a CC or MCC for inpatient DRG? +
Yes, this code is designated as CC. Documenting as a secondary diagnosis on inpatient claims can shift the DRG to a higher-weighted category.
What CPT codes are commonly billed with D68.021? +
Procedures frequently paired with D68.021 include: J7187, J7201, J7179, J7194, J7180.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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