ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D64.4

Billable / Specific

Congenital dyserythropoietic anemia

D64
Block
1
Synonyms
181
LCDs
8
Payer Policies
0
Linked CPTs

About ICD-10-CM D64.4

ICD-10-CM code D64.4 represents Congenital dyserythropoietic anemia. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D64). The 2026 edition of ICD-10-CM D64.4 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D64.4. Per CMS ICD-10-CM Tabular 2026.

  • Dyshematopoietic anemia (congenital)

Type 1 Excludes

Pure excludes, these codes can never be coded together with D64.4. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • Blackfan-Diamond syndrome (D61.01)
  • Di Guglielmo's disease (C94.0)

Medicare LCD Coverage for D64.4

Local Coverage Determinations (LCDs) from CMS MACs that list D64.4 as a covered diagnosis.

181 LCDs

Showing top 10 of 181 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0198U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81109 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0197U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0183U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81107 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0186U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81106 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0184U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0221U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0200U →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D64.4.

8 policies

5 Medicare

Billing and Coding: Lab: Flow Cytometry
Policy ID: ART-55717
Billing and Coding: Flow Cytometry
Policy ID: ART-56464
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57110
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57124
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57155

1 Aetna

Hematopoietic Cell Transplantation for Aplastic Anemia and other Bone Marrow Failure Syndromes
Policy ID: CPB-0627

CPT Codes Commonly Billed with D64.4

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for D64.4

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert D64.4 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D64.4 2858 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D64.4, Billing FAQ

Is ICD-10 code D64.4 billable? +

Yes, D64.4 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D64.4? +

ICD-10 D64.4 includes: Dyshematopoietic anemia (congenital).

What codes are Type 1 Excludes for D64.4? +

Type 1 Excludes (never code together with D64.4): Blackfan-Diamond syndrome (D61.01); Di Guglielmo's disease (C94.0)

What ICD-9 codes does D64.4 map to? +

Per CMS GEMs, D64.4 maps to ICD-9 codes: 2858. Useful for legacy data review and historical claim analysis.

Get the full PayerReady toolkit

Free access to CPT/ICD-10 lookup, denial appeals, fee comparator, and claim auditing with credentialing enrollment.

Start free →

Run this code through our claim audit tool

Check NCCI bundling, MUE limits, and modifier logic before submission.

Try the auditor →

Did this page help?

Quick signal so we know what to improve.

Thanks!

If you want a code reference page that doesn't exist yet, email coding@payerready.com.

Sorry to hear that.

Tell us what's missing or wrong: coding@payerready.com. We respond within 5 business days.

Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

Powered by 11K CPT · 98K ICD-10 · 860K MPFS rates · 4.5M NCCI edits · 9.5M NPIs. Our data methodology · About our coding team

Faster Approvals

Ready to Cut Your Enrollment Timeline in Half?

Join providers in all 50 states who handed off credentialing to a dedicated specialist. Create your free account in minutes and start enrolling the same day.

All 50 States Covered
No Long-Term Contracts
HIPAA HIPAA Compliant Platform
Dedicated Specialist Included