ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D64.3

Billable / Specific HCC v28: 48

Other sideroblastic anemias

D64
Block
2
Synonyms
191
LCDs
9
Payer Policies
0
Linked CPTs

About ICD-10-CM D64.3

ICD-10-CM code D64.3 represents Other sideroblastic anemias. This is a billable/specific code in the Blood and Blood-forming Organs chapter (block D64). The 2026 edition of ICD-10-CM D64.3 became effective on October 1, 2025.

Coding Tips for D64.3

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

D64.3 is a CMS-HCC v28 risk-adjustment code (category 48). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D64.3. Per CMS ICD-10-CM Tabular 2026.

  • Sideroblastic anemia NOS
  • Pyridoxine-responsive sideroblastic anemia NEC

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 48
ESRD-HCC
Category 48
RxHCC (Part D)
Category 48

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for D64.3

Local Coverage Determinations (LCDs) from CMS MACs that list D64.3 as a covered diagnosis.

191 LCDs

Showing top 10 of 191 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0198U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81109 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0197U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0183U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81107 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0186U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 81106 →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0184U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0221U →
CMS LCD: Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Article ID: 57155, Effective: 2024-10-01 00:00:00, 115 covered, 0 non-covered
CPT 0200U →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D64.3.

9 policies

5 Medicare

Billing and Coding: Lab: Flow Cytometry
Policy ID: ART-55717
Billing and Coding: Assays for Vitamins and Metabolic Function
Policy ID: ART-56416
Billing and Coding: Flow Cytometry
Policy ID: ART-56464
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57110
Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
Policy ID: ART-57124

1 Aetna

Therapeutic Phlebotomy
Policy ID: CPB-0652

CPT Codes Commonly Billed with D64.3

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

No procedure linkages on file for D64.3

We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.

Convert D64.3 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D64.3 2850 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D64.3, Billing FAQ

Is ICD-10 code D64.3 billable? +

Yes, D64.3 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D64.3? +

ICD-10 D64.3 includes: Sideroblastic anemia NOS; Pyridoxine-responsive sideroblastic anemia NEC.

Does D64.3 affect Medicare Advantage HCC risk adjustment? +

Yes. D64.3 maps to CMS-HCC v28 category 48. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What ICD-9 codes does D64.3 map to? +

Per CMS GEMs, D64.3 maps to ICD-9 codes: 2850. Useful for legacy data review and historical claim analysis.

Get the full PayerReady toolkit

Free access to CPT/ICD-10 lookup, denial appeals, fee comparator, and claim auditing with credentialing enrollment.

Start free →

Run this code through our claim audit tool

Check NCCI bundling, MUE limits, and modifier logic before submission.

Try the auditor →

Did this page help?

Quick signal so we know what to improve.

Thanks!

If you want a code reference page that doesn't exist yet, email coding@payerready.com.

Sorry to hear that.

Tell us what's missing or wrong: coding@payerready.com. We respond within 5 business days.

Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

Powered by 11K CPT · 98K ICD-10 · 860K MPFS rates · 4.5M NCCI edits · 9.5M NPIs. Our data methodology · About our coding team

Faster Approvals

Ready to Cut Your Enrollment Timeline in Half?

Join providers in all 50 states who handed off credentialing to a dedicated specialist. Create your free account in minutes and start enrolling the same day.

All 50 States Covered
No Long-Term Contracts
HIPAA HIPAA Compliant Platform
Dedicated Specialist Included