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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D48.7

Billable / Specific

Neoplasm of uncertain behavior of other specified sites

D48
Block
3
Synonyms
301
LCDs
25
Payer Policies
25
Linked CPTs

About ICD-10-CM D48.7

ICD-10-CM code D48.7 represents Neoplasm of uncertain behavior of other specified sites. This is a billable/specific code in the Neoplasms chapter (block D48). The 2026 edition of ICD-10-CM D48.7 became effective on October 1, 2025.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D48.7. Per CMS ICD-10-CM Tabular 2026.

  • Neoplasm of uncertain behavior of eye
  • Neoplasm of uncertain behavior of heart
  • Neoplasm of uncertain behavior of peripheral nerves of orbit

Type 1 Excludes

Pure excludes, these codes can never be coded together with D48.7. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • neoplasm of uncertain behavior of connective tissue (D48.1-)
  • neoplasm of uncertain behavior of skin of eyelid (D48.5)

Medicare LCD Coverage for D48.7

Local Coverage Determinations (LCDs) from CMS MACs that list D48.7 as a covered diagnosis.

301 LCDs

Showing top 10 of 301 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Article ID: 53060, Effective: 2025-10-01 00:00:00, 1692 covered, 0 non-covered
CPT 92201 →
CMS LCD: Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Article ID: 53060, Effective: 2025-10-01 00:00:00, 1692 covered, 0 non-covered
CPT 92250 →
CMS LCD: Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Article ID: 53060, Effective: 2025-10-01 00:00:00, 1692 covered, 0 non-covered
CPT 92202 →
CMS LCD: Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Article ID: 53060, Effective: 2025-10-01 00:00:00, 1692 covered, 0 non-covered
CPT 92227 →
CMS LCD: Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Article ID: 53060, Effective: 2025-10-01 00:00:00, 1692 covered, 0 non-covered
CPT 92228 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 93320 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 93313 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 93312 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 76376 →
CMS LCD: Billing and Coding: Transesophageal Echocardiography (TEE)
Article ID: 52868, Effective: 2025-01-01 00:00:00, 773 covered, 0 non-covered
CPT 93318 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D48.7.

25 policies

1 Aetna

Septoplasty and Rhinoplasty - Medical Clinical Policy Bulletins | Aetna
Policy ID: CPB-0005

5 Medicare

Oral Antiemetic Drugs (Replacement for Intravenous Antiemetics) - Policy Article
Policy ID: ART-52480
Billing and Coding: Transesophageal Echocardiography (TEE)
Policy ID: ART-52868
Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
Policy ID: ART-53060
Billing and Coding: Lab: Flow Cytometry
Policy ID: ART-55717
Billing and Coding: Erythropoiesis Stimulating Agents (ESA)
Policy ID: ART-56462

CPT Codes Commonly Billed with D48.7

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

25 linkages
  • Q9957 CMS LCD: Billing and Coding: Transthoracic Echocardiography (TTE) CMS LCD
  • Q9955 CMS LCD: Billing and Coding: Transthoracic Echocardiography (TTE) CMS LCD
  • C8923 CMS LCD: Billing and Coding: Transthoracic Echocardiography (TTE) CMS LCD
  • C8928 CMS LCD: Billing and Coding: Transthoracic Echocardiography (TTE) CMS LCD
  • C8924 CMS LCD: Billing and Coding: Transthoracic Echocardiography (TTE) CMS LCD
  • C8921 CMS LCD: Billing and Coding: Transthoracic Echocardiography (TTE) CMS LCD
  • 76376 CMS LCD: Billing and Coding: Transthoracic Echocardiography (TTE) CMS LCD
  • C8930 CMS LCD: Billing and Coding: Transthoracic Echocardiography (TTE) CMS LCD
  • C8929 CMS LCD: Billing and Coding: Transthoracic Echocardiography (TTE) CMS LCD
  • C8922 CMS LCD: Billing and Coding: Transthoracic Echocardiography (TTE) CMS LCD

Convert D48.7 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D48.7 2388 00000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D48.7, Billing FAQ

Is ICD-10 code D48.7 billable? +

Yes, D48.7 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D48.7? +

ICD-10 D48.7 includes: Neoplasm of uncertain behavior of eye; Neoplasm of uncertain behavior of heart; Neoplasm of uncertain behavior of peripheral nerves of orbit.

What codes are Type 1 Excludes for D48.7? +

Type 1 Excludes (never code together with D48.7): neoplasm of uncertain behavior of connective tissue (D48.1-); neoplasm of uncertain behavior of skin of eyelid (D48.5)

What CPT codes are commonly billed with D48.7? +

Procedures frequently paired with D48.7 include: Q9957, Q9955, C8923, C8928, C8924.

What ICD-9 codes does D48.7 map to? +

Per CMS GEMs, D48.7 maps to ICD-9 codes: 2388. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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