ICD-10 D48.1
Non-Billable HeaderNeoplasm of uncertain behavior of connective and other soft tissue
About ICD-10-CM D48.1
ICD-10-CM code D48.1 represents Neoplasm of uncertain behavior of connective and other soft tissue. This is a non-billable header code in the Neoplasms chapter (block D48). The 2026 edition of ICD-10-CM D48.1 became effective on October 1, 2025. Non-billable codes cannot be used as a primary or secondary diagnosis on a claim, use a more specific child code instead.
Inclusion Terms / Approximate Synonyms
Clinical terms and conditions classified under D48.1. Per CMS ICD-10-CM Tabular 2026.
- Neoplasm of uncertain behavior of connective tissue of ear
- Neoplasm of uncertain behavior of connective tissue of eyelid
- Stromal tumors of uncertain behavior of digestive system
Type 1 Excludes
Pure excludes, these codes can never be coded together with D48.1. The conditions are mutually exclusive (e.g., congenital vs acquired forms).
- neoplasm of uncertain behavior of articular cartilage (D48.0)
- neoplasm of uncertain behavior of cartilage of larynx (D38.0)
- neoplasm of uncertain behavior of cartilage of nose (D38.5)
- neoplasm of uncertain behavior of connective tissue of breast (D48.6-)
Medicare LCD Coverage for D48.1
Local Coverage Determinations (LCDs) from CMS MACs that list D48.1 as a covered diagnosis.
This doesn't mean the code isn't covered, it means no MAC has issued a Local Coverage Determination naming this specific code. Coverage may still apply under National Coverage Determinations or general medical-necessity rules.
Commercial Payer Coverage
Coverage policies from major commercial payers referencing D48.1.
Our payer policy database covers Aetna, Cigna, Anthem, BCBS, Humana, and Medicare Advantage plans, but D48.1 doesn't currently appear in any indexed policy. The code may still be covered under standard plan benefits.
CPT Codes Commonly Billed with D48.1
Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.
We don't have CPT pairings indexed for this specific code yet. Use the CPT search above to find common procedures, or check your payer's published medical policy for code-specific guidance.
Convert D48.1 to ICD-9-CM
Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.
| ICD-10 | ICD-9 | Mapping Flags |
|---|---|---|
| D48.1 | 2381 | 10000 |
Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).
Codes Adjacent To D48.1
Other codes in section D37-D48 (Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes).
ICD-10 D48.1, Billing FAQ
Is ICD-10 code D48.1 billable? +
No, D48.1 is a non-billable header code. Use a more specific child code from block D48 when submitting claims.
What other names or terms map to D48.1? +
ICD-10 D48.1 includes: Neoplasm of uncertain behavior of connective tissue of ear; Neoplasm of uncertain behavior of connective tissue of eyelid; Stromal tumors of uncertain behavior of digestive system.
What codes are Type 1 Excludes for D48.1? +
Type 1 Excludes (never code together with D48.1): neoplasm of uncertain behavior of articular cartilage (D48.0); neoplasm of uncertain behavior of cartilage of larynx (D38.0); neoplasm of uncertain behavior of cartilage of nose (D38.5)
What ICD-9 codes does D48.1 map to? +
Per CMS GEMs, D48.1 maps to ICD-9 codes: 2381. Useful for legacy data review and historical claim analysis.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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