PAYER READY CREDENTIALING & COMPLIANCE
ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D47.4

Billable / Specific HCC v28: 46

Osteomyelofibrosis

D47
Block
4
Synonyms
1,094
LCDs
30
Payer Policies
6
Linked CPTs

About ICD-10-CM D47.4

ICD-10-CM code D47.4 represents Osteomyelofibrosis. This is a billable/specific code in the Neoplasms chapter (block D47). The 2026 edition of ICD-10-CM D47.4 became effective on October 1, 2025.

Coding Tips for D47.4

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

D47.4 is a CMS-HCC v28 risk-adjustment code (category 46). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D47.4. Per CMS ICD-10-CM Tabular 2026.

  • Chronic idiopathic myelofibrosis
  • Myelofibrosis (idiopathic) (with myeloid metaplasia)
  • Myelosclerosis (megakaryocytic) with myeloid metaplasia
  • Secondary myelofibrosis in myeloproliferative disease

Type 1 Excludes

Pure excludes, these codes can never be coded together with D47.4. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • acute myelofibrosis (C94.4-)

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 46
ESRD-HCC
Category 46
RxHCC (Part D)
Category 46

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for D47.4

Local Coverage Determinations (LCDs) from CMS MACs that list D47.4 as a covered diagnosis.

1,094 LCDs

Showing top 10 of 1,094 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81215 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81300 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81351 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81167 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81405 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 0103U →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81201 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81297 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81298 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81299 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D47.4.

30 policies

1 Cigna

Flow Cytometry - (0538)
Policy ID: MM_0538

5 Medicare

Billing and Coding: Molecular Pathology Procedures
Policy ID: ART-56199
Billing and Coding: Flow Cytometry
Policy ID: ART-56464
Billing and Coding: Genomic Sequence Analysis Panels in the Treatment of Hematolymphoid Diseases
Policy ID: ART-56793
Billing and Coding: Erythropoiesis Stimulating Agents (ESAs)
Policy ID: ART-56795
Billing and Coding: MolDX: Next-Generation Sequencing Lab-Developed Tests for Myeloid Malignancies and Suspected Myeloid Malignancies
Policy ID: ART-57837

CPT Codes Commonly Billed with D47.4

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

6 linkages
  • 0027U CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD
  • 81270 CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD
  • 81338 CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD
  • 81339 CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD
  • 81219 CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD
  • 81279 CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD

Convert D47.4 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D47.4 28989 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D47.4, Billing FAQ

Is ICD-10 code D47.4 billable? +

Yes, D47.4 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D47.4? +

ICD-10 D47.4 includes: Chronic idiopathic myelofibrosis; Myelofibrosis (idiopathic) (with myeloid metaplasia); Myelosclerosis (megakaryocytic) with myeloid metaplasia, and 1 more clinical synonyms.

What codes are Type 1 Excludes for D47.4? +

Type 1 Excludes (never code together with D47.4): acute myelofibrosis (C94.4-)

Does D47.4 affect Medicare Advantage HCC risk adjustment? +

Yes. D47.4 maps to CMS-HCC v28 category 46. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What CPT codes are commonly billed with D47.4? +

Procedures frequently paired with D47.4 include: 0027U, 81270, 81338, 81339, 81219.

What ICD-9 codes does D47.4 map to? +

Per CMS GEMs, D47.4 maps to ICD-9 codes: 28989. Useful for legacy data review and historical claim analysis.

Get the full PayerReady toolkit

Free access to CPT/ICD-10 lookup, denial appeals, fee comparator, and claim auditing with credentialing enrollment.

Start free →

Run this code through our claim audit tool

Check NCCI bundling, MUE limits, and modifier logic before submission.

Try the auditor →

Did this page help?

Quick signal so we know what to improve.

Thanks!

If you want a code reference page that doesn't exist yet, email coding@payerready.com.

Sorry to hear that.

Tell us what's missing or wrong: coding@payerready.com. We respond within 5 business days.

Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

Powered by 11K CPT · 98K ICD-10 · 860K MPFS rates · 4.5M NCCI edits · 9.5M NPIs. Our data methodology · About our coding team

Every month un-credentialed is revenue you never bill

Sign up free, add your first provider, and watch the pipeline start moving this week.

Ask CredBrain

Answers from your credentialing team's verified knowledge base

Hi, I'm CredBrain. I answer from your credentialing team's verified knowledge base: payer join paths, state rules, timelines, associate billing, and enrollment workflows. If I don't have a verified answer, I'll say so and point you to your team. What would you like to know?

Try asking