ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D47.4

Billable / Specific HCC v28: 46

Osteomyelofibrosis

D47
Block
4
Synonyms
1,094
LCDs
30
Payer Policies
6
Linked CPTs

About ICD-10-CM D47.4

ICD-10-CM code D47.4 represents Osteomyelofibrosis. This is a billable/specific code in the Neoplasms chapter (block D47). The 2026 edition of ICD-10-CM D47.4 became effective on October 1, 2025.

Coding Tips for D47.4

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

D47.4 is a CMS-HCC v28 risk-adjustment code (category 46). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D47.4. Per CMS ICD-10-CM Tabular 2026.

  • Chronic idiopathic myelofibrosis
  • Myelofibrosis (idiopathic) (with myeloid metaplasia)
  • Myelosclerosis (megakaryocytic) with myeloid metaplasia
  • Secondary myelofibrosis in myeloproliferative disease

Type 1 Excludes

Pure excludes, these codes can never be coded together with D47.4. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • acute myelofibrosis (C94.4-)

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 46
ESRD-HCC
Category 46
RxHCC (Part D)
Category 46

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for D47.4

Local Coverage Determinations (LCDs) from CMS MACs that list D47.4 as a covered diagnosis.

1,094 LCDs

Showing top 10 of 1,094 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81215 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81300 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81351 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81167 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81405 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 0103U →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81201 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81297 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81298 →
CMS LCD: Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer
Article ID: 58679, Effective: 2026-02-05 00:00:00, 1346 covered, 0 non-covered
CPT 81299 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D47.4.

30 policies

1 Cigna

Flow Cytometry - (0538)
Policy ID: MM_0538

5 Medicare

Billing and Coding: Molecular Pathology Procedures
Policy ID: ART-56199
Billing and Coding: Flow Cytometry
Policy ID: ART-56464
Billing and Coding: Genomic Sequence Analysis Panels in the Treatment of Hematolymphoid Diseases
Policy ID: ART-56793
Billing and Coding: Erythropoiesis Stimulating Agents (ESAs)
Policy ID: ART-56795
Billing and Coding: MolDX: Next-Generation Sequencing Lab-Developed Tests for Myeloid Malignancies and Suspected Myeloid Malignancies
Policy ID: ART-57837

CPT Codes Commonly Billed with D47.4

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

6 linkages
  • 0027U CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD
  • 81270 CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD
  • 81338 CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD
  • 81339 CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD
  • 81219 CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD
  • 81279 CMS LCD: Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms CMS LCD

Convert D47.4 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D47.4 28989 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D47.4, Billing FAQ

Is ICD-10 code D47.4 billable? +

Yes, D47.4 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D47.4? +

ICD-10 D47.4 includes: Chronic idiopathic myelofibrosis; Myelofibrosis (idiopathic) (with myeloid metaplasia); Myelosclerosis (megakaryocytic) with myeloid metaplasia, and 1 more clinical synonyms.

What codes are Type 1 Excludes for D47.4? +

Type 1 Excludes (never code together with D47.4): acute myelofibrosis (C94.4-)

Does D47.4 affect Medicare Advantage HCC risk adjustment? +

Yes. D47.4 maps to CMS-HCC v28 category 46. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What CPT codes are commonly billed with D47.4? +

Procedures frequently paired with D47.4 include: 0027U, 81270, 81338, 81339, 81219.

What ICD-9 codes does D47.4 map to? +

Per CMS GEMs, D47.4 maps to ICD-9 codes: 28989. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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