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ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D43.9

Billable / Specific HCC v28: 12

Neoplasm of uncertain behavior of central nervous system, unspecified

D43
Block
1
Synonyms
86
LCDs
10
Payer Policies
2
Linked CPTs

About ICD-10-CM D43.9

ICD-10-CM code D43.9 represents Neoplasm of uncertain behavior of central nervous system, unspecified. This is a billable/specific code in the Neoplasms chapter (block D43). The 2026 edition of ICD-10-CM D43.9 became effective on October 1, 2025.

Coding Tips for D43.9

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

D43.9 is a CMS-HCC v28 risk-adjustment code (category 12). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D43.9. Per CMS ICD-10-CM Tabular 2026.

  • Neoplasm of uncertain behavior of nervous system (central) NOS

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 12
ESRD-HCC
Category 12
RxHCC (Part D)
Category 12

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for D43.9

Local Coverage Determinations (LCDs) from CMS MACs that list D43.9 as a covered diagnosis.

86 LCDs

Showing top 10 of 86 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64420 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 20561 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64415 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64447 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64448 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64416 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64405 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64454 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64425 →
CMS LCD: Billing and Coding: Peripheral Nerve Blocks
Article ID: 57452, Effective: 2025-10-01 00:00:00, 1570 covered, 0 non-covered
CPT 64450 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D43.9.

10 policies

2 Aetna

Magnetic Resonance Angiography (MRA) and Magnetic Resonance Venography (MRV) - Medical Clinical Policy Bulletins | Aetna
Policy ID: CPB-0094
Proton Beam, Neutron Beam, and Carbon Ion Radiotherapy
Policy ID: CPB-0270

1 Cigna

Neuropsychological Testing - (EN0258)
Policy ID: EN_MM_0258

5 Medicare

Oral Antiemetic Drugs (Replacement for Intravenous Antiemetics) - Policy Article
Policy ID: ART-52480
Billing and Coding: CT of the Head
Policy ID: ART-56612
Billing and Coding: Implantable Infusion Pump
Policy ID: ART-56695
Billing and Coding: Intraoperative Neurophysiological Testing
Policy ID: ART-56722
Billing and Coding: Somatosensory Testing
Policy ID: ART-57041

CPT Codes Commonly Billed with D43.9

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

2 linkages
  • 95940 CMS LCD: Billing and Coding: Intraoperative Neurophysiological Testing CMS LCD
  • G0453 CMS LCD: Billing and Coding: Intraoperative Neurophysiological Testing CMS LCD

Convert D43.9 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D43.9 2379 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D43.9, Billing FAQ

Is ICD-10 code D43.9 billable? +

Yes, D43.9 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D43.9? +

ICD-10 D43.9 includes: Neoplasm of uncertain behavior of nervous system (central) NOS.

Does D43.9 affect Medicare Advantage HCC risk adjustment? +

Yes. D43.9 maps to CMS-HCC v28 category 12. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What CPT codes are commonly billed with D43.9? +

Procedures frequently paired with D43.9 include: 95940, G0453.

What ICD-9 codes does D43.9 map to? +

Per CMS GEMs, D43.9 maps to ICD-9 codes: 2379. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on July 16, 2026.

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