ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 D43.0

Billable / Specific HCC v28: 12

Neoplasm of uncertain behavior of brain, supratentorial

D43
Block
6
Synonyms
321
LCDs
41
Payer Policies
7
Linked CPTs

About ICD-10-CM D43.0

ICD-10-CM code D43.0 represents Neoplasm of uncertain behavior of brain, supratentorial. This is a billable/specific code in the Neoplasms chapter (block D43). The 2026 edition of ICD-10-CM D43.0 became effective on October 1, 2025.

Coding Tips for D43.0

Specialist guidance from the PayerReady Medical Coding Team. Specificity warnings, HCC capture rules, sequencing notes.

HCC capture: document with MEAT each year

D43.0 is a CMS-HCC v28 risk-adjustment code (category 12). To count for the patient Risk Adjustment Factor (RAF), document the diagnosis with MEAT language each calendar year: Monitored, Evaluated, Assessed, Treated. A diagnosis on the problem list alone does not satisfy CMS RADV audit standards. Include the diagnosis in the assessment with current status and current treatment plan.

Inclusion Terms / Approximate Synonyms

Clinical terms and conditions classified under D43.0. Per CMS ICD-10-CM Tabular 2026.

  • Neoplasm of uncertain behavior of cerebral ventricle
  • Neoplasm of uncertain behavior of cerebrum
  • Neoplasm of uncertain behavior of frontal lobe
  • Neoplasm of uncertain behavior of occipital lobe
  • Neoplasm of uncertain behavior of parietal lobe
  • Neoplasm of uncertain behavior of temporal lobe

Type 1 Excludes

Pure excludes, these codes can never be coded together with D43.0. The conditions are mutually exclusive (e.g., congenital vs acquired forms).

  • neoplasm of uncertain behavior of fourth ventricle (D43.1)

Medicare Advantage HCC Impact

CMS-HCC v28 (current)
Category 12
ESRD-HCC
Category 12
RxHCC (Part D)
Category 12

Capture this diagnosis annually for accurate risk adjustment. Missed HCC captures are the #1 revenue leak in Medicare Advantage risk programs.

Medicare LCD Coverage for D43.0

Local Coverage Determinations (LCDs) from CMS MACs that list D43.0 as a covered diagnosis.

321 LCDs

Showing top 10 of 321 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77402 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77371 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 61797 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT G0339 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77338 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77432 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 61800 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77372 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77435 →
CMS LCD: Billing and Coding: Radiation Therapies
Article ID: 59350, Effective: 2026-01-01 00:00:00, 757 covered, 0 non-covered
CPT 77407 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing D43.0.

41 policies

2 Aetna

Back Pain - Invasive Procedures - Medical Clinical Policy Bulletins | Aetna
Policy ID: CPB-0016
Magnetic Resonance Angiography (MRA) and Magnetic Resonance Venography (MRV) - Medical Clinical Policy Bulletins | Aetna
Policy ID: CPB-0094

2 Cigna

Electrodiagnostic Testing (EMG/NCV) - (CPG129)
Policy ID: CPG129_EMG_NCV_SSEP
Neuropsychological Testing - (EN0258)
Policy ID: EN_MM_0258

5 Medicare

Billing and Coding: Bevacizumab and biosimilars
Policy ID: ART-52370
Oral Anticancer Drugs - Policy Article
Policy ID: ART-52479
Oral Antiemetic Drugs (Replacement for Intravenous Antiemetics) - Policy Article
Policy ID: ART-52480
Billing and Coding: Proton Beam Therapy
Policy ID: ART-55315
Billing and Coding: Erythropoiesis Stimulating Agents (ESA)
Policy ID: ART-56462

CPT Codes Commonly Billed with D43.0

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

7 linkages
  • 95926 CMS LCD: Billing and Coding: Somatosensory Testing CMS LCD
  • 95925 CMS LCD: Billing and Coding: Somatosensory Testing CMS LCD
  • 95938 CMS LCD: Billing and Coding: Somatosensory Testing CMS LCD
  • 95927 CMS LCD: Billing and Coding: Somatosensory Testing CMS LCD
  • 95940 CMS LCD: Billing and Coding: Intraoperative Neurophysiological Testing CMS LCD
  • G0453 CMS LCD: Billing and Coding: Intraoperative Neurophysiological Testing CMS LCD
  • 95941 CMS LCD: Billing and Coding: Intraoperative Neurophysiological Testing CMS LCD

Convert D43.0 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
D43.0 2375 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 D43.0, Billing FAQ

Is ICD-10 code D43.0 billable? +

Yes, D43.0 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What other names or terms map to D43.0? +

ICD-10 D43.0 includes: Neoplasm of uncertain behavior of cerebral ventricle; Neoplasm of uncertain behavior of cerebrum; Neoplasm of uncertain behavior of frontal lobe, and 3 more clinical synonyms.

What codes are Type 1 Excludes for D43.0? +

Type 1 Excludes (never code together with D43.0): neoplasm of uncertain behavior of fourth ventricle (D43.1)

Does D43.0 affect Medicare Advantage HCC risk adjustment? +

Yes. D43.0 maps to CMS-HCC v28 category 12. Capture this diagnosis annually for accurate Medicare Advantage risk score.

What CPT codes are commonly billed with D43.0? +

Procedures frequently paired with D43.0 include: 95926, 95925, 95938, 95927, 95940.

What ICD-9 codes does D43.0 map to? +

Per CMS GEMs, D43.0 maps to ICD-9 codes: 2375. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on June 1, 2026.

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