ICD-10-CM 2026 · Effective October 1, 2025

ICD-10 B27.00

Billable / Specific

Gammaherpesviral mononucleosis without complication

B27
Block
0
Synonyms
13
LCDs
2
Payer Policies
5
Linked CPTs

About ICD-10-CM B27.00

ICD-10-CM code B27.00 represents Gammaherpesviral mononucleosis without complication. This is a billable/specific code in the Infectious and Parasitic Diseases chapter (block B27). The 2026 edition of ICD-10-CM B27.00 became effective on October 1, 2025.

Medicare LCD Coverage for B27.00

Local Coverage Determinations (LCDs) from CMS MACs that list B27.00 as a covered diagnosis.

13 LCDs

Showing top 10 of 13 total . Click a CPT for full coverage scope.

CMS LCD: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions
Article ID: 55639, Effective: 2025-11-27 00:00:00, 564 covered, 0 non-covered
CPT Q5119 →
CMS LCD: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions
Article ID: 55639, Effective: 2025-11-27 00:00:00, 564 covered, 0 non-covered
CPT J9312 →
CMS LCD: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions
Article ID: 55639, Effective: 2025-11-27 00:00:00, 564 covered, 0 non-covered
CPT J9260 →
CMS LCD: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions
Article ID: 55639, Effective: 2025-11-27 00:00:00, 564 covered, 0 non-covered
CPT Q5123 →
CMS LCD: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions
Article ID: 55639, Effective: 2025-11-27 00:00:00, 564 covered, 0 non-covered
CPT Q5115 →
CMS LCD: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions
Article ID: 55639, Effective: 2025-11-27 00:00:00, 564 covered, 0 non-covered
CPT J9215 →
CMS LCD: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions
Article ID: 55639, Effective: 2025-11-27 00:00:00, 564 covered, 0 non-covered
CPT J9190 →
CMS LCD: Billing and Coding: Rituximab
Article ID: 56380, Effective: 2025-10-01 00:00:00, 692 covered, 0 non-covered
CPT J9311 →
CMS LCD: Billing and Coding: Rituximab
Article ID: 56380, Effective: 2025-10-01 00:00:00, 692 covered, 0 non-covered
CPT Q5119 →
CMS LCD: Billing and Coding: Rituximab
Article ID: 56380, Effective: 2025-10-01 00:00:00, 692 covered, 0 non-covered
CPT J9312 →

Commercial Payer Coverage

Coverage policies from major commercial payers referencing B27.00.

2 policies

2 Medicare

Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions
Policy ID: ART-55639
Billing and Coding: Rituximab
Policy ID: ART-56380

CPT Codes Commonly Billed with B27.00

Procedures frequently paired with this diagnosis based on PayerReady's Dx↔Px linkage data.

5 linkages
  • J9311 CMS LCD: Billing and Coding: Rituximab CMS LCD
  • J3590 CMS LCD: Billing and Coding: Rituximab CMS LCD
  • J9190 CMS LCD: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions CMS LCD
  • J9260 CMS LCD: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions CMS LCD
  • J9215 CMS LCD: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions CMS LCD

Convert B27.00 to ICD-9-CM

Per CMS General Equivalence Mappings (GEMs), useful for legacy data review and historical claim analysis.

ICD-10ICD-9Mapping Flags
B27.00 075 10000

Flags format (5 digits): Approximate · No Map · Combination · Scenario · Choice List. Source: CMS 2017 GEMs (final version).

ICD-10 B27.00, Billing FAQ

Is ICD-10 code B27.00 billable? +

Yes, B27.00 is a billable ICD-10-CM code that can appear as a primary or secondary diagnosis on claims.

What CPT codes are commonly billed with B27.00? +

Procedures frequently paired with B27.00 include: J9311, J3590, J9190, J9260, J9215.

What ICD-9 codes does B27.00 map to? +

Per CMS GEMs, B27.00 maps to ICD-9 codes: 075. Useful for legacy data review and historical claim analysis.

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Reviewed by the PayerReady Medical Coding Team

Verified against the CMS 2026 code set on May 31, 2026.

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