CPT 99448
Global XXX ActiveNtrprof ph1/ntrnet/ehr 21-30
CPT 99448 Billing & Documentation Guide
CPT code 99448 (Ntrprof ph1/ntrnet/ehr 21-30) is classified under E/M with a global period indicator of XXX. The 2026 Medicare Physician Fee Schedule assigns a work RVU of 1.05, a non-facility practice expense RVU of 0.56, and a malpractice RVU of 0.09, a total non-facility RVU of 1.7 and facility RVU of 1.43. With the current conversion factor of $33.4009, the national average non-facility reimbursement is approximately $57.88, though rates vary from $52.69 to $74.18 based on MAC locality and Geographic Practice Cost Indices (GPCIs).
When billing 99448, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 99448 with related codes; this code has 10 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Active code (paid under MPFS)
No global period (E/M and other non-procedural services)
MUE Limit (Medically Unlikely Edits)
Submitting more than 1 units of 99448 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
RVU Breakdown, CPT 99448
| Component | Non-Facility | Facility |
|---|---|---|
| Work RVU | 1.05 | 1.05 |
| Practice Expense RVU | 0.56 | 0.29 |
| Malpractice RVU | 0.09 | 0.09 |
| Total RVU | 1.7 | 1.43 |
| Conversion Factor | $33.4009 | |
2026 Medicare Reimbursement by State, CPT 99448
State-level averages across all MAC localities. Non-facility rates typically apply to office-based services; facility rates apply to hospital outpatient / inpatient.
| State | Non-Facility | Facility | Range (Non-Fac) | Localities |
|---|---|---|---|---|
| California | $60.09 | $49.42 | $57.78 - $67.51 | 29 |
| Florida | $59.69 | $50.64 | $57.47 - $62.14 | 3 |
| Georgia | $56.57 | $47.96 | $55.34 - $57.79 | 2 |
| Illinois | $59.01 | $50.3 | $56.85 - $61.01 | 4 |
| Michigan | $56.86 | $48.4 | $55.54 - $58.19 | 2 |
| North Carolina | $54.44 | $46.03 | $54.44 - $54.44 | 1 |
| New York | $61.69 | $51.63 | $54.95 - $65.14 | 5 |
| Ohio | $55.18 | $46.94 | $55.18 - $55.18 | 1 |
| Pennsylvania | $56.92 | $48.08 | $55.08 - $58.76 | 2 |
| Texas | $56.47 | $47.59 | $54.88 - $58.06 | 8 |
Source: CMS PFSRVU 2026 · Updated 2026-04-01. Full locality-level detail available for all 53 states, contact us for custom reports.
NCCI Bundling Edits, CPT 99448
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 99448 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 0359T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0360T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0361T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0362T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0363T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0364T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0365T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0366T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0367T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0368T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
Frequently Asked Questions, CPT 99448
What does CPT code 99448 mean? +
CPT code 99448 represents: Ntrprof ph1/ntrnet/ehr 21-30. It's in the E/M category with a global period of XXX.
What is the Medicare reimbursement for CPT 99448? +
The 2026 Medicare national average non-facility payment for CPT 99448 is $57.88. Rates range from $52.69 to $74.18 across 53 states depending on MAC locality and GPCIs.
What modifiers can I use with CPT 99448? +
E/M codes commonly use modifier 25 (significant separately identifiable E/M on same day as a procedure), 57 (decision for major surgery), 24 (unrelated E/M during global period), 95 (synchronous audio+video telehealth), 93 (audio-only telehealth), and AI (principal physician of record on admission). Surgical modifiers like 50, 51, 59 do not apply to E/M.
What bundling edits apply to CPT 99448? +
This code has 10 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 1, 2026.
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