CPT 99135
Global ZZZAnes comp ctrld hypotension
CMS assigns this code a status indicator of "B", meaning it is not separately payable under the Physician Fee Schedule. Payment is bundled into another procedure.
CPT 99135 Billing & Documentation Guide
CPT code 99135 (Anes comp ctrld hypotension) is classified under Anesthesia with a global period indicator of ZZZ. This code uses the Always bundled payment methodology rather than standard RVU-based Physician Fee Schedule pricing. Refer to the methodology notice above for billing implications.
When billing 99135, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 99135 with related codes; this code has 4 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Bundled code (no separate payment, included in another service)
Add-on code (global concept does not apply)
MUE Limit (Medically Unlikely Edits)
Submitting more than 0 units of 99135 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
NCCI Bundling Edits, CPT 99135
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 99135 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 36591 | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 36592 | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 96523 | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 00561 | Column 2 (secondary), bundled into primary | Yes | CPT Manual or CMS manual coding instruction |
Frequently Asked Questions, CPT 99135
What does CPT code 99135 mean? +
CPT code 99135 represents: Anes comp ctrld hypotension. It's in the Anesthesia category with a global period of ZZZ.
What is the Medicare reimbursement for CPT 99135? +
CMS assigns this code a status indicator of "B", meaning it is not separately payable under the Physician Fee Schedule. Payment is bundled into another procedure.
What modifiers can I use with CPT 99135? +
Medicine section spans a wide range: therapy services use GP/GO/GN (PT/OT/SLP plans of care) and KX (above cap with documentation). Drug administration uses JW (waste) and JZ (no waste). Professional/technical split applies to some diagnostic codes.
What bundling edits apply to CPT 99135? +
This code has 4 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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