CPT 95921
Global XXX ActiveAutonomic nrv parasym inervj
CPT 95921 Billing & Documentation Guide
CPT code 95921 (Autonomic nrv parasym inervj) is classified under Neurology with a global period indicator of XXX. The 2026 Medicare Physician Fee Schedule assigns a work RVU of 0.88, a non-facility practice expense RVU of 1.78, and a malpractice RVU of 0.04, a total non-facility RVU of 2.7 and facility RVU of 2.7. With the current conversion factor of $33.4009, the national average non-facility reimbursement is approximately $93.19, though rates vary from $81.15 to $119.07 based on MAC locality and Geographic Practice Cost Indices (GPCIs).
When billing 95921, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 95921 with related codes; this code has 10 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Active code (paid under MPFS)
No global period (E/M and other non-procedural services)
MUE Limit (Medically Unlikely Edits)
Submitting more than 1 units of 95921 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
RVU Breakdown, CPT 95921
| Component | Non-Facility | Facility |
|---|---|---|
| Work RVU | 0.88 | 0.88 |
| Practice Expense RVU | 1.78 | 1.78 |
| Malpractice RVU | 0.04 | 0.04 |
| Total RVU | 2.7 | 2.7 |
| Conversion Factor | $33.4009 | |
2026 Medicare Reimbursement by State, CPT 95921
State-level averages across all MAC localities. Non-facility rates typically apply to office-based services; facility rates apply to hospital outpatient / inpatient.
| State | Non-Facility | Facility | Range (Non-Fac) | Localities |
|---|---|---|---|---|
| California | $101.52 | $101.52 | $95.77 - $119.07 | 29 |
| Florida | $91.64 | $91.64 | $88.24 - $94.66 | 3 |
| Georgia | $87.76 | $87.76 | $84.02 - $91.49 | 2 |
| Illinois | $89.5 | $89.5 | $85.76 - $93.02 | 4 |
| Michigan | $87.1 | $87.1 | $85.18 - $89.02 | 2 |
| North Carolina | $85.72 | $85.72 | $85.72 - $85.72 | 1 |
| New York | $98.93 | $98.93 | $86.81 - $104.45 | 5 |
| Ohio | $85.02 | $85.02 | $85.02 - $85.02 | 1 |
| Pennsylvania | $89.32 | $89.32 | $85.23 - $93.41 | 2 |
| Texas | $89.33 | $89.33 | $84.74 - $93.54 | 8 |
Source: CMS PFSRVU 2026 · Updated 2026-04-01. Full locality-level detail available for all 53 states, contact us for custom reports.
NCCI Bundling Edits, CPT 95921
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 95921 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 0178T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0179T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0180T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0903T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0904T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0905T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 36140 | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 36591 | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 36592 | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 93000 | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
Frequently Asked Questions, CPT 95921
What does CPT code 95921 mean? +
CPT code 95921 represents: Autonomic nrv parasym inervj. It's in the Neurology category with a global period of XXX.
What is the Medicare reimbursement for CPT 95921? +
The 2026 Medicare national average non-facility payment for CPT 95921 is $93.19. Rates range from $81.15 to $119.07 across 53 states depending on MAC locality and GPCIs.
What modifiers can I use with CPT 95921? +
Medicine section spans a wide range: therapy services use GP/GO/GN (PT/OT/SLP plans of care) and KX (above cap with documentation). Drug administration uses JW (waste) and JZ (no waste). Professional/technical split applies to some diagnostic codes.
What bundling edits apply to CPT 95921? +
This code has 10 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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