CPT 87593
Global XXXOrthopoxvirus amp prb each
This code does not have a national work RVU on the current Physician Fee Schedule. Pricing may be carrier-determined, non-covered, or tracked via a separate methodology.
CPT 87593 Billing & Documentation Guide
CPT code 87593 (Orthopoxvirus amp prb each) is classified under Pathology/Lab with a global period indicator of XXX. This code uses the No national RVU payment methodology rather than standard RVU-based Physician Fee Schedule pricing. Refer to the methodology notice above for billing implications.
When billing 87593, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify current NCCI edits before bundling with related codes.
Payment Status & Global Period
Statutory exclusion
No global period (E/M and other non-procedural services)
MUE Limit (Medically Unlikely Edits)
Submitting more than 4 units of 87593 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
Frequently Asked Questions, CPT 87593
What does CPT code 87593 mean? +
CPT code 87593 represents: Orthopoxvirus amp prb each. It's in the Pathology/Lab category with a global period of XXX.
What is the Medicare reimbursement for CPT 87593? +
This code does not have a national work RVU on the current Physician Fee Schedule. Pricing may be carrier-determined, non-covered, or tracked via a separate methodology.
What modifiers can I use with CPT 87593? +
Pathology and laboratory use modifier 90 (reference/outside lab), 91 (repeat clinical diagnostic test same day), 92 (alternative laboratory platform), and QW (CLIA waived test). Surgical pathology splits between 26 and TC where applicable.
What bundling edits apply to CPT 87593? +
No NCCI PTP edits currently on file for this code.
Get the full PayerReady toolkit
Free access to CPT/ICD-10 lookup, denial appeals, fee comparator, and claim auditing with credentialing enrollment.
Start free →Run this code through our claim audit tool
Check NCCI bundling, MUE limits, and modifier logic before submission.
Try the auditor →Did this page help?
Quick signal so we know what to improve.
If you want a code reference page that doesn't exist yet, email coding@payerready.com.
Tell us what's missing or wrong: coding@payerready.com. We respond within 5 business days.
Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
Powered by 11K CPT · 98K ICD-10 · 860K MPFS rates · 4.5M NCCI edits · 9.5M NPIs. Our data methodology · About our coding team