CPT 77750
Global 090 ActiveInfuse radioactive materials
CPT 77750 Billing & Documentation Guide
CPT code 77750 (Infuse radioactive materials) is classified under Radiology with a global period indicator of 090. The 2026 Medicare Physician Fee Schedule assigns a work RVU of 4.88, a non-facility practice expense RVU of 6.7, and a malpractice RVU of 0.26, a total non-facility RVU of 11.84 and facility RVU of 11.84. With the current conversion factor of $33.4009, the national average non-facility reimbursement is approximately $407.31, though rates vary from $359.7 to $508.28 based on MAC locality and Geographic Practice Cost Indices (GPCIs).
When billing 77750, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 77750 with related codes; this code has 10 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Active code (paid under MPFS)
90-day global period (major surgery: 1 day pre-op + procedure + 90 days post-op)
MUE Limit (Medically Unlikely Edits)
Submitting more than 1 units of 77750 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
RVU Breakdown, CPT 77750
| Component | Non-Facility | Facility |
|---|---|---|
| Work RVU | 4.88 | 4.88 |
| Practice Expense RVU | 6.7 | 6.7 |
| Malpractice RVU | 0.26 | 0.26 |
| Total RVU | 11.84 | 11.84 |
| Conversion Factor | $33.4009 | |
2026 Medicare Reimbursement by State, CPT 77750
State-level averages across all MAC localities. Non-facility rates typically apply to office-based services; facility rates apply to hospital outpatient / inpatient.
| State | Non-Facility | Facility | Range (Non-Fac) | Localities |
|---|---|---|---|---|
| California | $438.35 | $438.35 | $415.69 - $508.28 | 29 |
| Florida | $404.43 | $404.43 | $389.99 - $417.92 | 3 |
| Georgia | $387.13 | $387.13 | $372.97 - $401.28 | 2 |
| Illinois | $396.4 | $396.4 | $380.89 - $409.35 | 4 |
| Michigan | $385.36 | $385.36 | $377.12 - $393.59 | 2 |
| North Carolina | $377.34 | $377.34 | $377.34 - $377.34 | 1 |
| New York | $432.19 | $432.19 | $381.7 - $455.64 | 5 |
| Ohio | $376.07 | $376.07 | $376.07 - $376.07 | 1 |
| Pennsylvania | $392.95 | $392.95 | $376.64 - $409.25 | 2 |
| Texas | $392.28 | $392.28 | $374.71 - $407.78 | 8 |
Source: CMS PFSRVU 2026 · Updated 2026-04-01. Full locality-level detail available for all 53 states, contact us for custom reports.
NCCI Bundling Edits, CPT 77750
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 77750 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 0213T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0216T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0228T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0230T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0591T | Column 1 (primary), can be billed with modifier | Yes | CPT Manual or CMS manual coding instruction |
| 0592T | Column 1 (primary), can be billed with modifier | Yes | CPT Manual or CMS manual coding instruction |
| 0593T | Column 1 (primary), can be billed with modifier | Yes | CPT Manual or CMS manual coding instruction |
| 0596T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0597T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0708T | Column 1 (primary), can be billed with modifier | 9 | Standards of medical/surgical practice |
Frequently Asked Questions, CPT 77750
What does CPT code 77750 mean? +
CPT code 77750 represents: Infuse radioactive materials. It's in the Radiology category with a global period of 090.
What is the Medicare reimbursement for CPT 77750? +
The 2026 Medicare national average non-facility payment for CPT 77750 is $407.31. Rates range from $359.7 to $508.28 across 53 states depending on MAC locality and GPCIs.
What modifiers can I use with CPT 77750? +
Radiology codes rely heavily on the professional/technical split: modifier 26 (professional component only) and TC (technical component only). Also common: 50 (bilateral imaging), 76 (repeat by same physician), 77 (repeat by different physician), and LT/RT for laterality.
What bundling edits apply to CPT 77750? +
This code has 10 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 2, 2026.
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