CPT 74280
Global XXX ActiveX-ray xm colon 2cntrst std
CPT 74280 Billing & Documentation Guide
CPT code 74280 (X-ray xm colon 2cntrst std) is classified under Radiology with a global period indicator of XXX. The 2026 Medicare Physician Fee Schedule assigns a work RVU of 1.23, a non-facility practice expense RVU of 5.01, and a malpractice RVU of 0.09, a total non-facility RVU of 6.33 and facility RVU of 6.33. With the current conversion factor of $33.4009, the national average non-facility reimbursement is approximately $219.14, though rates vary from $186.38 to $288.52 based on MAC locality and Geographic Practice Cost Indices (GPCIs).
When billing 74280, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 74280 with related codes; this code has 10 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Active code (paid under MPFS)
No global period (E/M and other non-procedural services)
MUE Limit (Medically Unlikely Edits)
Submitting more than 1 units of 74280 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
RVU Breakdown, CPT 74280
| Component | Non-Facility | Facility |
|---|---|---|
| Work RVU | 1.23 | 1.23 |
| Practice Expense RVU | 5.01 | 5.01 |
| Malpractice RVU | 0.09 | 0.09 |
| Total RVU | 6.33 | 6.33 |
| Conversion Factor | $33.4009 | |
2026 Medicare Reimbursement by State, CPT 74280
State-level averages across all MAC localities. Non-facility rates typically apply to office-based services; facility rates apply to hospital outpatient / inpatient.
| State | Non-Facility | Facility | Range (Non-Fac) | Localities |
|---|---|---|---|---|
| California | $242.19 | $242.19 | $226.8 - $288.52 | 29 |
| Florida | $214.83 | $214.83 | $205.58 - $222.88 | 3 |
| Georgia | $204.38 | $204.38 | $193.93 - $214.83 | 2 |
| Illinois | $208.66 | $208.66 | $198.56 - $218.55 | 4 |
| Michigan | $202.45 | $202.45 | $197.26 - $207.63 | 2 |
| North Carolina | $199.13 | $199.13 | $199.13 - $199.13 | 1 |
| New York | $233.8 | $233.8 | $202.17 - $248.26 | 5 |
| Ohio | $196.89 | $196.89 | $196.89 - $196.89 | 1 |
| Pennsylvania | $208.58 | $208.58 | $197.54 - $219.61 | 2 |
| Texas | $208.85 | $208.85 | $196.15 - $220.87 | 8 |
Source: CMS PFSRVU 2026 · Updated 2026-04-01. Full locality-level detail available for all 53 states, contact us for custom reports.
NCCI Bundling Edits, CPT 74280
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 74280 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 0868T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 36591 | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 36592 | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 74000 | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 74010 | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 74018 | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 74019 | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 74283 | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 76000 | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 76001 | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
Frequently Asked Questions, CPT 74280
What does CPT code 74280 mean? +
CPT code 74280 represents: X-ray xm colon 2cntrst std. It's in the Radiology category with a global period of XXX.
What is the Medicare reimbursement for CPT 74280? +
The 2026 Medicare national average non-facility payment for CPT 74280 is $219.14. Rates range from $186.38 to $288.52 across 53 states depending on MAC locality and GPCIs.
What modifiers can I use with CPT 74280? +
Radiology codes rely heavily on the professional/technical split: modifier 26 (professional component only) and TC (technical component only). Also common: 50 (bilateral imaging), 76 (repeat by same physician), 77 (repeat by different physician), and LT/RT for laterality.
What bundling edits apply to CPT 74280? +
This code has 10 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on April 17, 2026.
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