CPT 64480
Global ZZZ ActiveNjx aa&/strd tfrm epi c/t ea
CPT 64480 Billing & Documentation Guide
CPT code 64480 (Njx aa&/strd tfrm epi c/t ea) is classified under Surgery (Endocrine/Nervous/Eye/Ear) with a global period indicator of ZZZ. The 2026 Medicare Physician Fee Schedule assigns a work RVU of 1.17, a non-facility practice expense RVU of 3, and a malpractice RVU of 0.11, a total non-facility RVU of 4.28 and facility RVU of 1.59. With the current conversion factor of $33.4009, the national average non-facility reimbursement is approximately $147.6, though rates vary from $127.05 to $189.84 based on MAC locality and Geographic Practice Cost Indices (GPCIs).
When billing 64480, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 64480 with related codes; this code has 10 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Active code (paid under MPFS)
Add-on code (global concept does not apply)
MUE Limit (Medically Unlikely Edits)
Submitting more than 4 units of 64480 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
RVU Breakdown, CPT 64480
| Component | Non-Facility | Facility |
|---|---|---|
| Work RVU | 1.17 | 1.17 |
| Practice Expense RVU | 3 | 0.31 |
| Malpractice RVU | 0.11 | 0.11 |
| Total RVU | 4.28 | 1.59 |
| Conversion Factor | $33.4009 | |
2026 Medicare Reimbursement by State, CPT 64480
State-level averages across all MAC localities. Non-facility rates typically apply to office-based services; facility rates apply to hospital outpatient / inpatient.
| State | Non-Facility | Facility | Range (Non-Fac) | Localities |
|---|---|---|---|---|
| California | $161.04 | $54.72 | $151.53 - $189.84 | 29 |
| Florida | $146.77 | $56.62 | $140.4 - $152.68 | 3 |
| Georgia | $139.13 | $53.41 | $132.84 - $145.41 | 2 |
| Illinois | $143.06 | $56.24 | $136.31 - $148.77 | 4 |
| Michigan | $138.34 | $53.98 | $134.71 - $141.97 | 2 |
| North Carolina | $134.92 | $51.09 | $134.92 - $134.92 | 1 |
| New York | $157.71 | $57.48 | $136.85 - $167.54 | 5 |
| Ohio | $134.27 | $52.24 | $134.27 - $134.27 | 1 |
| Pennsylvania | $141.51 | $53.5 | $134.54 - $148.48 | 2 |
| Texas | $141.36 | $52.9 | $133.68 - $148.43 | 8 |
Source: CMS PFSRVU 2026 · Updated 2026-04-01. Full locality-level detail available for all 53 states, contact us for custom reports.
NCCI Bundling Edits, CPT 64480
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 64480 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 01991 | Column 1 (primary), can be billed with modifier | No | Anesthesia service included in surgical procedure |
| 01992 | Column 1 (primary), can be billed with modifier | No | Anesthesia service included in surgical procedure |
| 0229T | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 0282T | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 0283T | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 0284T | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 0285T | Column 1 (primary), can be billed with modifier | No | CPT Manual or CMS manual coding instruction |
| 0333T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0464T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0543T | Column 1 (primary), can be billed with modifier | No | Misuse of Column Two code with Column One code |
Frequently Asked Questions, CPT 64480
What does CPT code 64480 mean? +
CPT code 64480 represents: Njx aa&/strd tfrm epi c/t ea. It's in the Surgery (Endocrine/Nervous/Eye/Ear) category with a global period of ZZZ.
What is the Medicare reimbursement for CPT 64480? +
The 2026 Medicare national average non-facility payment for CPT 64480 is $147.6. Rates range from $127.05 to $189.84 across 53 states depending on MAC locality and GPCIs.
What modifiers can I use with CPT 64480? +
Surgery codes commonly use modifier 22 (increased procedural services), 50 (bilateral), 51 (multiple procedures), 52 (reduced services), 58/78/79 (staged, unplanned return, unrelated within global), 62 (co-surgeons), 80/82 (assistant surgeon), and 59 or the X{EPSU} subset for distinct procedural service.
What bundling edits apply to CPT 64480? +
This code has 10 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 1, 2026.
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