CPT 45334
Global 000 ActiveSigmoidoscopy for bleeding
CPT 45334 Billing & Documentation Guide
CPT code 45334 (Sigmoidoscopy for bleeding) is classified under Surgery (Digestive) with a global period indicator of 000. The 2026 Medicare Physician Fee Schedule assigns a work RVU of 1.95, a non-facility practice expense RVU of 14.12, and a malpractice RVU of 0.22, a total non-facility RVU of 16.29 and facility RVU of 3.17. With the current conversion factor of $33.4009, the national average non-facility reimbursement is approximately $564.95, though rates vary from $474.04 to $756.31 based on MAC locality and Geographic Practice Cost Indices (GPCIs).
When billing 45334, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 45334 with related codes; this code has 10 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Active code (paid under MPFS)
Endoscopic or minor procedure with related preoperative and postoperative work performed on the same day
MUE Limit (Medically Unlikely Edits)
Submitting more than 1 units of 45334 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
RVU Breakdown, CPT 45334
| Component | Non-Facility | Facility |
|---|---|---|
| Work RVU | 1.95 | 1.95 |
| Practice Expense RVU | 14.12 | 1 |
| Malpractice RVU | 0.22 | 0.22 |
| Total RVU | 16.29 | 3.17 |
| Conversion Factor | $33.4009 | |
2026 Medicare Reimbursement by State, CPT 45334
State-level averages across all MAC localities. Non-facility rates typically apply to office-based services; facility rates apply to hospital outpatient / inpatient.
| State | Non-Facility | Facility | Range (Non-Fac) | Localities |
|---|---|---|---|---|
| California | $629.51 | $110.97 | $587.07 - $756.31 | 29 |
| Florida | $552.63 | $112.95 | $527.05 - $574.67 | 3 |
| Georgia | $523.95 | $105.89 | $494.58 - $553.32 | 2 |
| Illinois | $535.11 | $111.67 | $507.21 - $562.96 | 4 |
| Michigan | $518.33 | $106.84 | $504.02 - $532.63 | 2 |
| North Carolina | $509.85 | $100.99 | $509.85 - $509.85 | 1 |
| New York | $604.35 | $115.47 | $518.34 - $643.7 | 5 |
| Ohio | $503.13 | $103.03 | $503.13 - $503.13 | 1 |
| Pennsylvania | $535.53 | $106.29 | $505.02 - $566.03 | 2 |
| Texas | $536.63 | $105.2 | $501.13 - $570.75 | 8 |
Source: CMS PFSRVU 2026 · Updated 2026-04-01. Full locality-level detail available for all 53 states, contact us for custom reports.
NCCI Bundling Edits, CPT 45334
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 45334 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 00731 | Column 1 (primary), can be billed with modifier | No | Anesthesia service included in surgical procedure |
| 00732 | Column 1 (primary), can be billed with modifier | No | Anesthesia service included in surgical procedure |
| 00740 | Column 1 (primary), can be billed with modifier | No | Anesthesia service included in surgical procedure |
| 00810 | Column 1 (primary), can be billed with modifier | No | Anesthesia service included in surgical procedure |
| 00811 | Column 1 (primary), can be billed with modifier | No | Anesthesia service included in surgical procedure |
| 00812 | Column 1 (primary), can be billed with modifier | No | Anesthesia service included in surgical procedure |
| 00813 | Column 1 (primary), can be billed with modifier | No | Anesthesia service included in surgical procedure |
| 0184T | Column 1 (primary), can be billed with modifier | No | More extensive procedure |
| 0213T | Column 1 (primary), can be billed with modifier | No | Misuse of Column Two code with Column One code |
| 0216T | Column 1 (primary), can be billed with modifier | No | Misuse of Column Two code with Column One code |
Frequently Asked Questions, CPT 45334
What does CPT code 45334 mean? +
CPT code 45334 represents: Sigmoidoscopy for bleeding. It's in the Surgery (Digestive) category with a global period of 000.
What is the Medicare reimbursement for CPT 45334? +
The 2026 Medicare national average non-facility payment for CPT 45334 is $564.95. Rates range from $474.04 to $756.31 across 53 states depending on MAC locality and GPCIs.
What modifiers can I use with CPT 45334? +
Surgery codes commonly use modifier 22 (increased procedural services), 50 (bilateral), 51 (multiple procedures), 52 (reduced services), 58/78/79 (staged, unplanned return, unrelated within global), 62 (co-surgeons), 80/82 (assistant surgeon), and 59 or the X{EPSU} subset for distinct procedural service.
What bundling edits apply to CPT 45334? +
This code has 10 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 1, 2026.
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