CPT 29581
Global 000 ActiveAppl multlayer cmprn sys leg
CPT 29581 Billing & Documentation Guide
CPT code 29581 (Appl multlayer cmprn sys leg) is classified under Surgery (Musculoskeletal) with a global period indicator of 000. The 2026 Medicare Physician Fee Schedule assigns a work RVU of 0.59, a non-facility practice expense RVU of 1.9, and a malpractice RVU of 0.01, a total non-facility RVU of 2.5 and facility RVU of 0.69. With the current conversion factor of $33.4009, the national average non-facility reimbursement is approximately $86.63, though rates vary from $74.39 to $113.57 based on MAC locality and Geographic Practice Cost Indices (GPCIs).
When billing 29581, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 29581 with related codes; this code has 10 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Active code (paid under MPFS)
Endoscopic or minor procedure with related preoperative and postoperative work performed on the same day
MUE Limit (Medically Unlikely Edits)
Submitting more than 1 units of 29581 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
RVU Breakdown, CPT 29581
| Component | Non-Facility | Facility |
|---|---|---|
| Work RVU | 0.59 | 0.59 |
| Practice Expense RVU | 1.9 | 0.09 |
| Malpractice RVU | 0.01 | 0.01 |
| Total RVU | 2.5 | 0.69 |
| Conversion Factor | $33.4009 | |
2026 Medicare Reimbursement by State, CPT 29581
State-level averages across all MAC localities. Non-facility rates typically apply to office-based services; facility rates apply to hospital outpatient / inpatient.
| State | Non-Facility | Facility | Range (Non-Fac) | Localities |
|---|---|---|---|---|
| California | $95.68 | $24.15 | $89.77 - $113.57 | 29 |
| Florida | $84.03 | $23.37 | $80.88 - $86.61 | 3 |
| Georgia | $80.68 | $23.01 | $76.71 - $84.64 | 2 |
| Illinois | $81.73 | $23.31 | $78.17 - $85.61 | 4 |
| Michigan | $79.77 | $23 | $78.02 - $81.51 | 2 |
| North Carolina | $79.13 | $22.72 | $79.13 - $79.13 | 1 |
| New York | $91.89 | $24.45 | $80.23 - $97.04 | 5 |
| Ohio | $77.98 | $22.79 | $77.98 - $77.98 | 1 |
| Pennsylvania | $82.4 | $23.19 | $78.28 - $86.52 | 2 |
| Texas | $82.6 | $23.08 | $77.77 - $87.18 | 8 |
Source: CMS PFSRVU 2026 · Updated 2026-04-01. Full locality-level detail available for all 53 states, contact us for custom reports.
NCCI Bundling Edits, CPT 29581
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 29581 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 0213T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0216T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0228T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0230T | Column 1 (primary), can be billed with modifier | No | Standards of medical/surgical practice |
| 0596T | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 0597T | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 0708T | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 0709T | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 0903T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0904T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
Frequently Asked Questions, CPT 29581
What does CPT code 29581 mean? +
CPT code 29581 represents: Appl multlayer cmprn sys leg. It's in the Surgery (Musculoskeletal) category with a global period of 000.
What is the Medicare reimbursement for CPT 29581? +
The 2026 Medicare national average non-facility payment for CPT 29581 is $86.63. Rates range from $74.39 to $113.57 across 53 states depending on MAC locality and GPCIs.
What modifiers can I use with CPT 29581? +
Surgery codes commonly use modifier 22 (increased procedural services), 50 (bilateral), 51 (multiple procedures), 52 (reduced services), 58/78/79 (staged, unplanned return, unrelated within global), 62 (co-surgeons), 80/82 (assistant surgeon), and 59 or the X{EPSU} subset for distinct procedural service.
What bundling edits apply to CPT 29581? +
This code has 10 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on June 1, 2026.
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