CPT 15777
Global ZZZ ActiveAcellular derm matrix implt
CPT 15777 Billing & Documentation Guide
CPT code 15777 (Acellular derm matrix implt) is classified under Anesthesia with a global period indicator of ZZZ. The 2026 Medicare Physician Fee Schedule assigns a work RVU of 3.56, a non-facility practice expense RVU of 2.48, and a malpractice RVU of 0.67, a total non-facility RVU of 6.71 and facility RVU of 5.46. With the current conversion factor of $33.4009, the national average non-facility reimbursement is approximately $226.94, though rates vary from $201.59 to $278.91 based on MAC locality and Geographic Practice Cost Indices (GPCIs).
When billing 15777, ensure documentation supports medical necessity and the specific components required for the code's level of service. For E/M codes, document MDM (medical decision-making) elements: problems addressed, data reviewed, and risk. For procedural codes, document the indication, technique, and any complications. Always verify NCCI edits before bundling 15777 with related codes; this code has 10 PTP bundling relationships on file (see table below).
Payment Status & Global Period
Active code (paid under MPFS)
Add-on code (global concept does not apply)
MUE Limit (Medically Unlikely Edits)
Submitting more than 1 units of 15777 for the same patient on the same date triggers automatic line denial unless an appropriate modifier and supporting documentation justify the higher quantity.
RVU Breakdown, CPT 15777
| Component | Non-Facility | Facility |
|---|---|---|
| Work RVU | 3.56 | 3.56 |
| Practice Expense RVU | 2.48 | 1.23 |
| Malpractice RVU | 0.67 | 0.67 |
| Total RVU | 6.71 | 5.46 |
| Conversion Factor | $33.4009 | |
2026 Medicare Reimbursement by State, CPT 15777
State-level averages across all MAC localities. Non-facility rates typically apply to office-based services; facility rates apply to hospital outpatient / inpatient.
| State | Non-Facility | Facility | Range (Non-Fac) | Localities |
|---|---|---|---|---|
| California | $233.32 | $183.92 | $223.71 - $263.43 | 29 |
| Florida | $245.58 | $203.69 | $231.73 - $261.73 | 3 |
| Georgia | $224.89 | $185.06 | $219.47 - $230.3 | 2 |
| Illinois | $242.13 | $201.79 | $229.51 - $254.35 | 4 |
| Michigan | $228.19 | $188.98 | $219.8 - $236.57 | 2 |
| North Carolina | $210.49 | $171.54 | $210.49 - $210.49 | 1 |
| New York | $247.38 | $200.8 | $213.33 - $266.56 | 5 |
| Ohio | $217.09 | $178.97 | $217.09 - $217.09 | 1 |
| Pennsylvania | $225.04 | $184.14 | $216.1 - $233.98 | 2 |
| Texas | $221.9 | $180.8 | $215.08 - $232.91 | 8 |
Source: CMS PFSRVU 2026 · Updated 2026-04-01. Full locality-level detail available for all 53 states, contact us for custom reports.
NCCI Bundling Edits, CPT 15777
Procedure-to-procedure (PTP) edits. If you bill any of these codes with 15777 on the same date of service, review the modifier indicator and payer policy before submission.
| Partner Code | Relationship | Modifier Allowed | Rationale |
|---|---|---|---|
| 0213T | Column 1 (primary), can be billed with modifier | No | Misuse of Column Two code with Column One code |
| 0216T | Column 1 (primary), can be billed with modifier | No | Misuse of Column Two code with Column One code |
| 0228T | Column 1 (primary), can be billed with modifier | No | Misuse of Column Two code with Column One code |
| 0230T | Column 1 (primary), can be billed with modifier | No | Misuse of Column Two code with Column One code |
| 0437T | Column 1 (primary), can be billed with modifier | Yes | CPT Manual or CMS manual coding instruction |
| 0596T | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 0597T | Column 1 (primary), can be billed with modifier | Yes | Standards of medical/surgical practice |
| 0903T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0904T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
| 0905T | Column 1 (primary), can be billed with modifier | Yes | Misuse of Column Two code with Column One code |
Frequently Asked Questions, CPT 15777
What does CPT code 15777 mean? +
CPT code 15777 represents: Acellular derm matrix implt. It's in the Anesthesia category with a global period of ZZZ.
What is the Medicare reimbursement for CPT 15777? +
The 2026 Medicare national average non-facility payment for CPT 15777 is $226.94. Rates range from $201.59 to $278.91 across 53 states depending on MAC locality and GPCIs.
What modifiers can I use with CPT 15777? +
Surgery codes commonly use modifier 22 (increased procedural services), 50 (bilateral), 51 (multiple procedures), 52 (reduced services), 58/78/79 (staged, unplanned return, unrelated within global), 62 (co-surgeons), 80/82 (assistant surgeon), and 59 or the X{EPSU} subset for distinct procedural service.
What bundling edits apply to CPT 15777? +
This code has 10 NCCI PTP bundling relationships. See the NCCI Bundling section below for full list.
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Reviewed by the PayerReady Medical Coding Team
Verified against the CMS 2026 code set on May 31, 2026.
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